Protein Alignment CG34384 and dgk-2

DIOPT Version :10

• Sequence 1: NP_001246971.1
• Gene: CG34384 / 5740362
• FlyBaseID: FBgn0085413
• Length: 1936
• Species: Drosophila melanogaster
• Sequence 2: NP_001024679.1
• Gene: dgk-2 / 180720
• WormBaseID: WBGene00000959
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 139/516 - (26%)
• Similarity: 228/516 - (44%)
• Gaps: 96/516 - (18%)

  Fly   196 HHW----YATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKD 256
            |:|    |:..|   .||:.|::.:..    |..|:.|..||..       .||    |.:|...
 Worm    47 HYWSSINYSEQH---NYCSGCKEHIVS----GYECDNCLLKVDN-------INC----LRAVSTK 93

  Fly   257 IIEQADGI-----IMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAV 316
            |..:.:.|     ...|.|:.||:.....|.||::.||.| .|||:||.||...||..|:|:...
 Worm    94 IQCKVNPIHCRKETFDHHWICGNIGADLFCEVCEELCGGV-GLQDFRCSWCWRVVHTKCKPKFTK 157

  Fly   317 ACPIGPAKLSVVPPTSV---------HSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLR 372
            .|..|..|.:::||..|         ..::..|..::......:.|::|.||.|||...|.:.||
 Worm   158 HCDFGGLKRTIIPPYCVTTRRPGNRNQRMAVIDKIEIPVDIEKWRPIMVIVNPKSGSGAGKQLLR 222

  Fly   373 RFKQLLNPAQVFDLISTGPSLGLR-LFRHFEM-FRILVCSGDGSVGWVLSEIDRFNMHKQCQVAV 435
            .|:..|:||||.|::.:..:..|| :..|..: .|||:..|||::...|.:||  .:.::..|||
 Worm   223 NFRAHLHPAQVVDVLKSNIAASLRWIDEHPNVDVRILIAGGDGTICSALDQID--TLSRRIPVAV 285

  Fly   436 MPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSI-MVFEKAIPV----PKTPKM 495
            :||||||||:|:|.||..||.|..:.:::|..:.|...::|||:| ...:|.:.|    .||..|
 Worm   286 LPLGTGNDLSRLLKWGKKCDGDIDVIKLMEDIQEAEVTLVDRWTIDAESQKKLGVRLQSNKTLSM 350

  Fly   496 S--ISTEQEAMLT-GMVTS------------ANHHLRFIVETNDTQTLIRSTRNLCDTVDDLVCR 545
            :  :|...:|.:| ||..:            .|..|.|...|.|  ...|..:.|.:.:|..:..
 Worm   351 TNYVSVGVDACVTLGMQNTRESIPRAMSSRLLNKFLFFTFGTKD--VFERVCKGLNERIDLYLDD 413

  Fly   546 ISEHHKDDEQL---------------AVKCDILRQKLN--MLLDALQEEEIGAHSGDDLIATIRS 593
            :..:..|.|.|               |...|..||:.:  |:       |:.|.:....||.::.
 Worm   414 VHVNLPDIEGLIFLNIPYWGAGVKPWATYNDSHRQECDDEMI-------EVFAVTSSFHIAQMQI 471

  Fly   594 LIARSIPVTPGSNAYLL---NPNISIEKTEKDQINT------KERRNSRSLRSSEKEALQC 645
            .:|..:.:....:|.|:   |.:..::...:..:|:      ..:..:..||.:||:...|
 Worm   472 GLASPLCIGQAKHAKLVFKGNHSFPMQSDGEAWVNSAGTVLISHKCKTAMLRKAEKQTTGC 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34384	NP_001246971.1	PH_DGK_type2	84..180	CDD:270093
		C1_DGK_typeII_rpt1	192..251	CDD:410350	14/58 (24%)
		C1_DGK_typeII_rpt2	268..321	CDD:410402	22/52 (42%)
		DAGKc	355..477	CDD:214487	48/123 (39%)
		DAGKa	1478..1635	CDD:214486
		SAM_DGK-delta-eta	1869..1933	CDD:188906
dgk-2	NP_001024679.1	C1_DGKepsilon_typeIII_rpt1	44..98	CDD:410351	17/68 (25%)
		C1_DGKepsilon_typeIII_rpt2	110..171	CDD:410403	24/61 (39%)
		DAGK_cat	203..325	CDD:425868	49/123 (40%)
		DAGK_acc	350..503	CDD:470579	30/161 (19%)