DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spok and CYP76C6

DIOPT Version :9

Sequence 1:	NP_001104460.2	Gene:	spok / 5740359	FlyBaseID:	FBgn0086917	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_174633.1	Gene:	CYP76C6 / 840263	AraportID:	AT1G33720	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	573	Identity:	129/573 - (22%)
Similarity:	223/573 - (38%)	Gaps:	115/573 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ILISYVFLLLKCKQKAFVVIGLLY------QEKKYQCFDQAPGPHPWPIIGNINLLGRFQYNPFY 75
            |:......|:.|    |::..||:      :....|.....|||...||||||:|:|:   ||.:
plant     3 IISGQPLFLIFC----FILSCLLFFTTARSRRSPCQLSKSPPGPPRLPIIGNIHLVGK---NPHH 60

  Fly    76 GFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNK-----NGKYFGGRPDFFRYHKLFGGDRN 135
            .|..|:|.||.:.||.||....:|:.:.|.::|||..     :|:|.........:|:...|
plant    61 SFTDLSKTYGPVMSLKLGCLNSVVIASRDAVREVLKTHDQILSGRYISEATKSNNHHEFSVG--- 122

  Fly   136 NSLALCDWSQLQQKRRNLARR---------HCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSG 191
                   |......|..:.|:         .|.....:....|:.|:    ||.|.:......:
plant   123 -------WIHPSSSRFRMLRKLSATQLFSPQCIQATKALRMKKVQEL----VNFLSESCEREEA- 175

  Fly   192 YPCDVKPLILAASANMFCQYMCSVRF-NYSDK---GFQKIIEYFDEIFWEINQGYSFDYIPWLVP 252
              .|:..:....:.|:....:.||.. :|..|   .||:::..:.|   .|......::.|::..
plant   176 --VDISHVSFVTALNIISNILFSVNLGSYDSKNSSAFQEMVIGYQE---SIGNPDLANFFPFMRF 235

  Fly   253 FYCNHISRIVHWSAS-----IRKFILERIVNHRESNININEPDKDFTDALLKSLKEDK-NVSRNT 311
            ......|:.:..|:.     .|:|...|||.....::..:...|||.|.|:...:.|: .::.:.
plant   236 LDLQGNSKKMRESSGRLLQVFREFYDARIVEKSSRSVEKDVSSKDFLDVLIDLQQGDETEINIDE 300

  Fly   312 IIFMLED-FIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPYTMA 375
            |..:|.| |:.|.....:.|..|:|.:..||.....:::|::.|..:. ......|::.:||..|
plant   301 IEHLLLDMFVAGTDTNSSTVEWAMAELLGNPKTMTKVQDEINHVIGQN-GDFQESDISKLPYLKA 364

  Fly   376 SISEVLR-YSSSPIVPHVAMEDTV-IKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPERFLEN 438
            .:.|..| :.::|.:.....|..| |.||.|.|.:.|.:|.:.:......|.:|..|:|||||
plant   365 VVKETFRLHPAAPFLLQRKAETNVEILGFTVLKDSQVLVNVWAIGRDPLVWENPTHFEPERFL-- 427

  Fly   439 NFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRTCIGQ 503
                .||..:|..|.:.|                                   ||..|:|.|.|.
plant   428 ----GKEIDVKGTDYELT-----------------------------------PFGAGRRICPGL 453

  Fly   504 SLVRGFGFLLLANIIQNY------NVNSADFSK-----IKLEKSS--IALPKK 543
            .|......|:||:::..:      .|.|.|...     :.:.|::  :|:|.|
plant   454 PLAMKTVHLMLASLLYTFEWKLPNGVGSEDLDMEETFGLTVHKTNPLLAVPLK 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	122/532 (23%)
CYP76C6	NP_174633.1	p450	11..504	CDD:299894	126/561 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000