Protein Alignment spok and Cyp2c23

DIOPT Version :10

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_114027.2
• Gene: Cyp2c23 / 83790
• RGDID: 620370
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 140/588 - (23%)
• Similarity: 243/588 - (41%)
• Gaps: 141/588 - (23%)

  Fly     7 YVLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQY 71
            :...|:.:::..:|.:.:..|.:.:     |.|           .|||.|.|||||:     .|.
  Rat     6 FTTLALVVSVTCLSLLSVWTKLRTR-----GRL-----------PPGPTPLPIIGNL-----LQL 49

  Fly    72 N----PFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGR---PDFFRYHKL 129
            |    | .....|.|:||.:|:|..|.:..:|::..|::||.|.:.|..|.||   |.....||.
  Rat    50 NLKDIP-ASLSKLAKEYGPVYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKG 113

  Fly   130 FG-----GDRNNSLALCDWSQLQQ------KRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLD 183
            :|     |:|        |..:::      :...:.:|....|...            |...|::
  Rat   114 YGLIFSNGER--------WKVMRRFSLMTLRNFGMGKRSLEERVQE------------EARCLVE 158

  Fly   184 QLTNISSGYPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGYSFDYIP 248
            :|.. :...|.|...::..|..|:.|..:.:.||.|::|.|..:::..::.|.::|..:...|..
  Rat   159 ELQK-TKAQPFDPTFILACAPCNVICSILFNDRFQYNNKTFLNLMDLLNKNFQQVNSVWCQMYNL 222

  Fly   249 W--LVPF----YCNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKSLKEDKNV 307
            |  ::.:    :.....||    ..::.||||::..|::|....|  .:|:.|..|..::|:|:.
  Rat   223 WPTIIKYLPGKHIEFAKRI----DDVKNFILEKVKEHQKSLDPAN--PRDYIDCFLSKIEEEKDN 281

  Fly   308 SRNTIIFMLED--------FIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICL 364
            .::.  |.||:        |..|.......:...|..:.|.|.:...:..|:|.|..:. :...:
  Rat   282 LKSE--FHLENLAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQAKVHEELDRVIGRH-QPPSM 343

  Fly   365 YDMNVMPYTMASISEVLRY----SSSPIVPHVAMEDTVIKGFGVRKGTIV--FINNYVLNMSESF 423
            .|...:|||.|.:.|:.||    .||  :||..::||..:.:.:.|||.|  .:::.:|:..|
  Rat   344 KDKMKLPYTDAVLHEIQRYITLLPSS--LPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKE-- 404

  Fly   424 WNHPEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIP 488
            :.:||:|||..||:.|                          |..|...|
  Rat   405 FANPEKFDPGHFLDKN--------------------------GCFKKTDY--------------- 428

  Fly   489 QFLPFSVGKRTCIGQSLVRGFGFLLLANIIQNYN----VNSADFSKIKLEKSSIALPKKCFKLSL 549
             |:|||:|||.|:|:||.|...||....::|.::    |...|.....:....|.||.. :||.|
  Rat   429 -FVPFSLGKRACVGESLARMELFLFFTTLLQKFSLKTLVEPKDLDIKPITTGIINLPPP-YKLCL 491

  Fly   550 RPR 552
            .||
  Rat   492 VPR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	CYP1_2-like	85..547	CDD:410710	115/499 (23%)
Cyp2c23	NP_114027.2	CYP2C-like	65..489	CDD:410758	116/500 (23%)