DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spok and CYP71B10

DIOPT Version :9

Sequence 1:	NP_001104460.2	Gene:	spok / 5740359	FlyBaseID:	FBgn0086917	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_200536.3	Gene:	CYP71B10 / 835831	AraportID:	AT5G57260	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	129/545 - (23%)
Similarity:	230/545 - (42%)	Gaps:	112/545 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYN 72
            ||:.::: |:|||.:.:.:|..::.:|              .|.|.|...|||||::.||..
plant     3 VLWFVSL-ILLISILLVAVKHSKRRWV--------------RQPPSPPGLPIIGNLHQLGEL--- 49

  Fly    73 PFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKLFGGDRNNS 137
            |......|:||||.:..|.||....::|:..:..|:||.....:...||......||.....:.:
plant    50 PHQSLCKLSKKYGPVMLLKLGRVPTVIVSTPETAKQVLKDYDLHCCSRPSLEGTRKLSYNYLDIA 114

  Fly   138 LALCD--WSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPCDVKPLI 200
            .:..|  |.:|  ::..:....|:.|.:|     :..|...|:.:|:|.:...:|     .|.|:
plant   115 FSRFDDYWKEL--RKLCVEELFCNKRINS-----IQPIKEAEMEKLIDSIAESAS-----QKTLV 167

  Fly   201 ------LAASANMFCQYMCSVRFN----YSDKGFQKIIEYFDEIFWEINQGYSFDYIPWLVPFYC 255
                  |:.:.|:.|:.:..|.|.    .:|| ||.::....|:....:....|.|:.|:|.::.
plant   168 NLSDTFLSLNVNVICKAVFGVNFQGTVLNNDK-FQDLVHEALEMLGSFSASDFFPYVGWIVDWFT 231

  Fly   256 N-HISRIVHWSASIR---KFILERIVNHRESNININEPDKDFTDALLKSLKEDK-----NVSRNT 311
            . |..|    ..|:|   .|..:.|..|.:.  |..|.:.||.|.||:..||:.     .::||.
plant   232 GLHARR----ERSVRDLDAFYEQMIDLHLQK--NREESEDDFVDLLLRLEKEEAVLGYGKLTRNH 290

  Fly   312 I-IFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKG--IRRICLYDMNVMPYT 373
            | ..::...:||.:.....:..|:|.:.:||.:...:::|:.....|.  .|.|.|.::|.:.|.
plant   291 IKAILMNILLGGINTSAITMTWAMAELIRNPRVMKKVQSEIRAQIGKNNKTRIISLDEINHLSYL 355

  Fly   374 MASISEVLR-YSSSP-IVPHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPERFL 436
            ...|.|..| :..:| :||...:.:..|.|:.::..|.:.:|.:.:......|..||:|.||||:
plant   356 NMVIKETCRLHPVAPLLVPREVISEFKINGYTIQPKTRLHVNVWAIGRDPEIWKDPEEFLPERFM 420

  Fly   437 ENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRTC- 500
            :            ||.:              .|.:.|               :.|||..|:|.|
plant   421 D------------CDID--------------VKGQDY---------------ELLPFGSGRRICP 444

  Fly   501 ---IGQSLVRGFGFLLLANIIQNYN 522
               :|.:.|. ||   |||::.:::
plant   445 AVYMGITTVE-FG---LANLLYHFD 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	120/501 (24%)
CYP71B10	NP_200536.3	CYP71-like	60..493	CDD:410695	108/470 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910