DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spok and CYP71B12

DIOPT Version :9

Sequence 1:	NP_001104460.2	Gene:	spok / 5740359	FlyBaseID:	FBgn0086917	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_197895.1	Gene:	CYP71B12 / 832584	AraportID:	AT5G25130	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	584	Identity:	126/584 - (21%)
Similarity:	220/584 - (37%)	Gaps:	138/584 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYNPFYG 76
            :::..|::::||.      .:.:::.::.:.||    :..|||...|||||::.||.   .|...
plant     1 MSLWYIIVAFVFF------SSMIIVRIIRKTKK----NLPPGPPRLPIIGNLHQLGS---KPHRS 52

  Fly    77 FGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPD---------------FFRY 126
            ...|::.||.:.||..|....:|.:..:.:||||.........||:               |..|
plant    53 MFKLSETYGPLMSLKFGSVSTVVASTPETVKEVLKTFDVECCSRPNMTYPARVTYNLKDLCFSPY 117

  Fly   127 HKLFGGDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSG 191
            .|.             |.::  ::..:...:.:.|..|...::..|:..|.  ..:.|..::..
plant   118 SKY-------------WREV--RKMTVVELYTAKRVQSFQHTRKEEVAALV--DFIKQAASLEK- 164

  Fly   192 YPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGY-----SF---DYIP 248
             |.::...::..|.::.|:    |.|..:.:| .|:...::|:.    ||.     ||   ||.|
plant   165 -PVNLNKKLMKLSGSVICR----VAFGINLQG-SKLENTYEEVI----QGTVELVGSFAAADYFP 219

  Fly   249 WLVPFYCNHISRIVHWSASIRK-------FILERIVNHRESNININEPDKDFTDALLK------S 300
            .:...    |.||....:...|       |..:.|.:|.|..| |.:   |..|.|||      :
plant   220 VVGRI----IDRITGLHSKCEKLFKAMDAFFDQSIKHHLEDEI-IKD---DIIDLLLKMERGETT 276

  Fly   301 LKEDKNVSRNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLY 365
            |.|.:....:|...:......|......::...:.|:..||.:....:.||..| .|....|...
plant   277 LGEFQLTRDHTKGILANILNAGIDTSAQVMTWVMTYLISNPRVLKKAQAEVREV-IKHKDDIIEE 340

  Fly   366 DMNVMPYTMASISEVLRYSSSPIV----PHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNH 426
            |:..:.|....|.|..|.  :|:|    |..|.:|..|.|:.:.|.|.:.:|.:.::.:.:.|..
plant   341 DIERLQYLKMVIKETFRI--NPLVPLLIPREASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVWKD 403

  Fly   427 PEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFL 491
            ||.|.||||:::..           |.|...|                              :.|
plant   404 PEAFIPERFMDSQI-----------DYKGLNF------------------------------ELL 427

  Fly   492 PFSVGKRTCIGQSLVRGFGFLLLANIIQNYNVNSADFSK---IKLEKS-SIALPKKCFKLSLRP 551
            ||..|:|.|.|..:......|.|.|::..::....:..|   :.||:| .:..||| ..|.|.|
plant   428 PFGSGRRICPGIGMGMALVHLTLINLLYRFDWKLPEGMKVADVDLEESYGLVCPKK-IPLQLIP 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	119/540 (22%)
CYP71B12	NP_197895.1	p450	1..490	CDD:386267	125/582 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000