DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spok and CYP81F4

DIOPT Version :9

Sequence 1:	NP_001104460.2	Gene:	spok / 5740359	FlyBaseID:	FBgn0086917	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_195457.1	Gene:	CYP81F4 / 829895	AraportID:	AT4G37410	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	558	Identity:	115/558 - (20%)
Similarity:	222/558 - (39%)	Gaps:	128/558 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VFYVLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGP-HPWPIIGNINLLGR 68
            :|..:..:.:.:.|::|.|.....||:.::                .|.| :..||:|:..|:..
plant     1 MFNYVIILPLALFLLAYKFFFTSKKQRYYL----------------PPSPSYSLPILGHHLLIKP 49

  Fly    69 FQYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVL-NKNGKYFGGRPDF-------FR 125
            ..:..|:   .|:..:|.|:.|.||..|.:|:::..|.:|.. .:|......||.|       :.
plant    50 PVHRLFH---RLSNIHGPIFYLRLGSRRAVVISSSSLARECFTGQNDVIVSNRPRFLTSKYIAYN 111

  Fly   126 YHKLFG---GDRNNSLALCDWSQLQQKRRNLARRHCSPR-ESSSYFSKMSEIGGLEVNQLLDQLT 186
            |..:..   ||.        |       ||| ||.||.. .||...:....|...|:.::|.:|:
plant   112 YTTIATTSYGDH--------W-------RNL-RRICSLEIVSSKRLANFLHIRKEEIQRMLTRLS 160

  Fly   187 -NISSGYPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEI--NQG--YSFDY 246
             :...|...:::.::...:.|...:.:....:...|...::..|.|.::|..|  |.|  :..:|
plant   161 RDARVGKEVELESILYDLTFNNIVRMVTGKIYYGDDVSDKEEAELFKKLFTFITTNSGARHPGEY 225

  Fly   247 IPWLVPFYCNHISRIVHWSASIRKFILERIVNHRESN----------ININEPDKD-FTDALLKS 300
            :|:: ..:.....:.|..:|.:...:|:|:::..:|:          :::.:.|.: :||.::|.
plant   226 LPFM-KIFGGSFEKEVKAAAKVIDEMLQRLLDECKSDKDGNTMVNHLLSLQQDDPEYYTDIIIKG 289

  Fly   301 LKEDKNVSRNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLY 365
            |             ||...:.........:..|:|.:..:|.:...::.|:|.:..:. |.|...
plant   290 L-------------MLGIMVASSETSALTIEWAMASLLNHPKVLDKVKLEIDEIIGQD-RLIEES 340

  Fly   366 DMNVMPYTMASISEVLR-YSSSPI-VPHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPE 428
            |:..:||....:||.|| :.::|: ||....||..|.|:.|.:.|:|.:|.:.::.....|..||
plant   341 DIANLPYLQNVVSETLRLHPAAPVLVPRSTAEDIKIGGYDVPRDTMVMVNAWAIHRDPDLWTEPE 405

  Fly   429 QFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPF 493
            :|:||||                          |..:|.                |..:...:.|
plant   406 RFNPERF--------------------------NGGEGE----------------KDDVRMLIAF 428

  Fly   494 SVGKRTCIGQSLVRGFGFLLLANIIQNYNVNSADFSKI 531
            ..|:|.|.|..|......|.|.::||.:     |:.|:
plant   429 GSGRRICPGVGLAHKIVTLALGSLIQCF-----DWKKV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	109/511 (21%)
CYP81F4	NP_195457.1	CYP81	63..482	CDD:410746	101/477 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000