DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spok and CYP81H1

DIOPT Version :9

Sequence 1:	NP_001104460.2	Gene:	spok / 5740359	FlyBaseID:	FBgn0086917	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_568024.2	Gene:	CYP81H1 / 829886	AraportID:	AT4G37310	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	144/565 - (25%)
Similarity:	232/565 - (41%)	Gaps:	123/565 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPH-PWPIIGNINLLGRFQYNPFY--GFGTLTKK 83
            :.|:|......|:|..:|...|..:  :..|.|: .:||||:::||.:    |..  ....|:..
plant     4 ILLILTTLVAIFIVKIVLLVTKPNK--NLPPSPNICFPIIGHLHLLKK----PLLHRTLSHLSHS 62

  Fly    84 YGDIYSLSLGHTRCIVVNNVDLIKE-VLNKNGKYFGGRPDF-------FRYHKLFG---GDRNNS 137
            .|.::||.||....:::::....:| .|.||......||.|       :.|..:..   ||.
plant    63 LGPVFSLRLGSRLAVIISSPTAAEECFLTKNDIVLANRPRFIMGKYVAYDYTSMVTAPYGDH--- 124

  Fly   138 LALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPC--DVKPLI 200
                 |       |||.|.......|::..:..:||...||..||.:|.::|...|.  :::.|:
plant   125 -----W-------RNLRRITALEVFSTNRLNASAEIRHDEVKMLLQKLHDLSVERPAKVELRQLL 177

  Fly   201 LAASANMFCQYMCSVRFNYSDKG--------FQKIIEYFDEIFWEINQGYSFDYIPWLVPF-YCN 256
            ...:.|:..:.|...||...|.|        |::::....|:....|..   |::|.|..| |..
plant   178 TGLTLNVIMRMMTGKRFFEEDDGGKAGISLEFRELVAEILELSAADNPA---DFLPALRWFDYKG 239

  Fly   257 HISRIVHWSASIRKFILERIVNHRESNININEPDKD---FTDALLKSL-----KEDKNVSRNTI- 312
            .:.|        .|.|.||:.:..:..::.:..:||   |.:.::..|     ||..|.|..||
plant   240 LVKR--------AKRIGERMDSLLQGFLDEHRANKDRLEFKNTMIAHLLDSQEKEPHNYSDQTIK 296

  Fly   313 --IFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDT-VSAKGIRRIC----LYDMNVM 370
              |.|:  .:||.......|..|::.:..:|.|....|..:|| :.....||:.    |.:||
plant   297 GLILMM--VVGGTDTSALTVEWAMSNLLNHPQILETTRQNIDTQMETSSSRRLLKEEDLVNMN-- 357

  Fly   371 PYTMASISEVLR-YSSSPI-VPHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPE 433
             |....:||.|| |..:|: ||||...|.||.||.|.:.|||.:|.:.::...|.|:.|..|.||
plant   358 -YLKNVVSETLRLYPVAPLMVPHVPSSDCVIGGFNVPRDTIVLVNLWAIHRDPSVWDDPTSFKPE 421

  Fly   434 RFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKR 498
            ||                             :||.:...|     |.|:        :||.:|:|
plant   422 RF-----------------------------EGSDQFGHY-----NGKM--------MPFGLGRR 444

  Fly   499 TCIGQSLVRGFGFLLLANIIQNYNVNSADFSKIKL-EKSSIALPK 542
            .|.|.||......|||.::||.:...|....::.: |...::|||
plant   445 ACPGLSLANRVVGLLLGSMIQCFEWESGSGGQVDMTEGPGLSLPK 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	138/535 (26%)
CYP81H1	NP_568024.2	p450	6..500	CDD:299894	144/563 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000