DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spok and CYP82G1

DIOPT Version :9

Sequence 1:	NP_001104460.2	Gene:	spok / 5740359	FlyBaseID:	FBgn0086917	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_189154.1	Gene:	CYP82G1 / 822110	AraportID:	AT3G25180	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	568	Identity:	135/568 - (23%)
Similarity:	226/568 - (39%)	Gaps:	118/568 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFAIAITIILISYVFL---LLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHP---WPIIGNINLLG 67
            ||::|  :::..|:||   |.:|:                  .|.:..|.|   .|:.|:::||
plant    12 LFSLA--LVIFGYIFLRKQLSRCE------------------VDSSTIPEPLGALPLFGHLHLL- 55

  Fly    68 RFQYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPD--FFRYHKLF 130
            |.:.........:::|:|.|:||.||..|.:|.::...:|:....|......||:  |.||
plant    56 RGKKLLCKKLAAMSQKHGPIFSLKLGFYRLVVASDPKTVKDCFTTNDLATATRPNIAFGRY---- 116

  Fly   131 GGDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYP-C 194
            .|..|.||.|..:....::.|.:...|.....|   ...:..|...|||.|:..|...:.|.. .
plant   117 VGYNNASLTLAPYGDYWRELRKIVTVHLFSNHS---IEMLGHIRSSEVNTLIKHLYKGNGGTSIV 178

  Fly   195 DVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGYSF-----------DYIP 248
            .:..|....:.|:..:.|...|.     ||.::..  ||  |...:....           |.||
plant   179 KIDMLFEFLTFNIILRKMVGKRI-----GFGEVNS--DE--WRYKEALKHCEYLAVIPMIGDVIP 234

  Fly   249 WL--VPFYCN-HISRIVHWSASIR-KFILERIVNHRESNININEPDKDFT--DALLKSLKEDKNV 307
            ||  :.|..| .:.|:.....|:. |::.|.:.....     ||.|::.|  |.||..|.||..:
plant   235 WLGWLDFAKNSQMKRLFKELDSVNTKWLHEHLKKRSR-----NEKDQERTIMDLLLDILPEDIVI 294

  Fly   308 S---RNTII--FMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDM 367
            |   |:.|:  .:|...:.|..:....:..|::.:..||......:.|:|....|| |.|...|:
plant   295 SGHVRDVIVKATILALTLTGSDSTSITLTWAVSLLLNNPAALEAAQEEIDNSVGKG-RWIEESDI 358

  Fly   368 NVMPYTMASISEVLR-YSSSPIVP-HVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQF 430
            ..:.|..|.:.|..| |..:|:.. ..|.||..:.|:.|.|||.:.:|.:.|:.....|..|:.|
plant   359 QNLKYLQAIVKETHRLYPPAPLTGIREAREDCFVGGYRVEKGTRLLVNIWKLHRDPKIWPDPKTF 423

  Fly   431 DPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSV 495
            .||||:|:                              ||:           .:||..:::||..
plant   424 KPERFMED------------------------------KSQ-----------CEKSNFEYIPFGS 447

  Fly   496 GKRTCIGQSLVRGFGFLLLANIIQNYNVNSADFSKIKL-EKSSIALPK 542
            |:|:|.|.:|.......:||.::|.:.::......:.: |...:||||
plant   448 GRRSCPGVNLGLRVVHFVLARLLQGFELHKVSDEPLDMAEGPGLALPK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	126/522 (24%)
CYP82G1	NP_189154.1	p450	8..514	CDD:299894	135/568 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000