DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spok and CYP71B6

DIOPT Version :9

Sequence 1:	NP_001104460.2	Gene:	spok / 5740359	FlyBaseID:	FBgn0086917	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_179995.1	Gene:	CYP71B6 / 816952	AraportID:	AT2G24180	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	135/566 - (23%)
Similarity:	235/566 - (41%)	Gaps:	126/566 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYNP 73
            ||:..|:..|:.::.|||   ....::..||...|     :..|||...||:|||:.||..   |
plant     3 LFSFPISTELLPWLLLLL---IPPLLIFFLLRSPK-----NLPPGPPRLPILGNIHQLGSL---P 56

  Fly    74 FYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDF-----FRYHKLFGGD 133
            ......|:.|||.:.::.||..|.:||::.:..:|||..:......||..     |.|..|
plant    57 HRSLRDLSLKYGPVITVYLGSVRTVVVHSPETAEEVLKLHDSECCTRPKLSITKSFFYDGL---- 117

  Fly   134 RNNSLALCDWSQLQQKRRNLARRHC-----SPRESSSYFSKMSEIGGLEVNQLLDQLT-NISSGY 192
               .|....|....:..|.|    |     |.:.::|:.:...|    |:::|::..: :.|||.
plant   118 ---GLGFTKWGDYYRDVRKL----CVLELFSVKRANSFRNIREE----ELSRLVNSFSDSASSGS 171

  Fly   193 PCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGY----SFDYIP---WL 250
            ..|    :.|..|.....:.|.:.|..|.:|.....|.|.|:|.|.|:..    :.|..|   |:
plant   172 SVD----LTANLAKFVASFTCRMAFGLSFQGSGMDNETFLELFTEANRVIGKFAAADIFPGFGWI 232

  Fly   251 VPFYCNHISRIVHWSASIRK-------FILERIVNHRESNININEPDKDFTDALLKSLKEDKNVS 308
                   :.||....:|.||       |..:.||:|||.  ...|..:|..|.|||...::..:.
plant   233 -------LDRISGLDSSRRKSFQDLDTFYQKAIVDHREK--KKTEDREDLIDVLLKLQSQETKLG 288

  Fly   309 RNTI------IFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEV-DTVSAKGIRRICLYD 366
            .:.|      ..:::.|:.|.......:...:|.::::|.:...::.|: :.|..|||  :...|
plant   289 SSRITDTHIRAIIMDLFVAGVDTSVITLDWTMAELSRHPRVMKKVQAEIREHVGDKGI--VTYDD 351

  Fly   367 MNVMPYTMASISEVLR-YSSSPI-VPHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQ 429
            :..:.|....|.|..| ::.||| :|..||.:..|||:.:..||.:.:|.:.:..:...|..|::
plant   352 LEALVYMKMVIKETWRLHAPSPILIPREAMTNFKIKGYDIYPGTRIHVNAWAIGRNPDVWKDPDE 416

  Fly   430 FDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFS 494
            |.||||:::|.           :.|.|.|                              :.|||.
plant   417 FIPERFVDSNV-----------ETKGTSF------------------------------ELLPFG 440

  Fly   495 VGKRTC----IGQSLVRGFGFLLLANIIQNYNVNSADFSKIKLEKS 536
            .|:|.|    :|.|.|.    ..|||::.:::..:.:  ::.:|::
plant   441 SGRRGCPAMYVGLSTVE----YTLANLLYHFDWKATE--EVSVEEA 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	125/523 (24%)
CYP71B6	NP_179995.1	p450	36..499	CDD:299894	125/525 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000