Protein Alignment spok and Cyp2d26

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_083838.1
• Gene: Cyp2d26 / 76279
• MGIID: 1923529
• Length: 500
• Species: Mus musculus
• Alignment Length: 537
• Identity: 126/537 - (23%)
• Similarity: 230/537 - (42%)
• Gaps: 100/537 - (18%)

  Fly    16 IILISYVFLLLKCKQKAFVVIGLLYQEKKY-QCFDQAPGPHPWPIIGNINLLGRFQYNPFYGFGT 79
            :::.:.:||||         :.|:::.::: .|:  .|||.|:|.:||: |...|:..| |.|..
Mouse    12 VVIFTAIFLLL---------VDLVHRRQRWTACY--PPGPVPFPGLGNL-LQVDFENIP-YSFYK 63

  Fly    80 LTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKLFGGDRNNSLALC--- 141
            |..:||:::||.:.....:|||.:..::|:|...|:....||....|:.:..|.::..:.|.
Mouse    64 LQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSKGVILAPYG 128

  Fly   142 -DWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPCDVKPLILAASA 205
             :|.  :|:|.:::..........|....::|    |...|.|..|. .:.:|.:..||:..|.:
Mouse   129 PEWR--EQRRFSVSTLRDFGLGKKSLEQWVTE----EAGHLCDAFTK-EAEHPFNPSPLLSKAVS 186

  Fly   206 NMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEIN--QGYSFDYIPWLVPFYCNHI--------SR 260
            |:....:.:.||.|.|..|.::::...|...|..  .|...:.||.|:     ||        .:
Mouse   187 NVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLL-----HIPGLPDKAFPK 246

  Fly   261 IVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKSLKEDKN------VSRNTIIFMLEDF 319
            :..:.|.:.|.::|     .:|..:..:|.:|.|||.|..:::.|.      ..:|..|.:::.|
Mouse   247 LNSFIALVNKMLIE-----HDSTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDKNLRIVVIDLF 306

  Fly   320 IGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPYTMASISEVLRYS 384
            :.|.......:..||..:..:|.:...:..|:|.|... :|...:.|...||||.|.|.||.|::
Mouse   307 MAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEVIGH-VRHPEMADQARMPYTNAVIHEVQRFA 370

  Fly   385 SSPIV----PHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPERFLENNFTNNKE 445
            .  ||    ||:...|...:.|.:.|||.:..|...:...|:.|..|.:|.||.||:
Mouse   371 D--IVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYPEHFLD-------- 425

  Fly   446 SGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRTCIGQSLVRGFG 510
                    .:..|::..                          .|:|||.|:|:|:|:.|.|...
Mouse   426 --------AQGHFVKHE--------------------------AFMPFSAGRRSCLGEPLARMEL 456

  Fly   511 FLLLANIIQNYNVNSAD 527
            ||....::|.::.:..|
Mouse   457 FLFFTCLLQRFSFSVPD 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	120/500 (24%)
Cyp2d26	NP_083838.1	p450	37..496	CDD:278495	120/501 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920