Protein Alignment spok and Cyp2s1

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_083051.1
• Gene: Cyp2s1 / 74134
• MGIID: 1921384
• Length: 501
• Species: Mus musculus
• Alignment Length: 574
• Identity: 136/574 - (23%)
• Similarity: 231/574 - (40%)
• Gaps: 127/574 - (22%)

  Fly     4 SVFYVLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGR 68
            |.:.:|.|:.:.::|:|  ..|.:...:.::                .|||.|.|::||:
Mouse     5 STWALLLALLLLLLLLS--LTLFRTPARGYL----------------PPGPTPLPLLGNL----- 46

  Fly    69 FQYNP---FYGFGTLTKKYGDIYSLSLG-HTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKL 129
            .|..|   :.|...|:||||.::::.|| ..|.:|:...|.::|.|....:.|.||.......|.
Mouse    47 LQLRPGALYSGLLRLSKKYGPVFTVYLGPWRRVVVLVGHDAVREALGGQAEEFSGRGTLATLDKT 111

  Fly   130 F--------GGDRNNSLALCDWSQLQQKRRNLARRH--CSPRESSSYFSKMSEIGGLEVNQLLDQ 184
            |        .|:|        |.|| :|...||.|.  ...||.       .|:...||..|::.
Mouse   112 FDGHGVFFANGER--------WKQL-RKFTLLALRDLGMGKREG-------EELIQAEVQSLVEA 160

  Fly   185 LTNISSGYPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQ--GYSFDYI 247
            ... :.|.|.:...|:..|::|:.|..:..:|..|.||.||.:|:........|:.  |.:::..
Mouse   161 FQK-TEGRPFNPSMLLAQATSNVVCSLVFGIRLPYDDKEFQAVIQAASGTLLGISSPWGQAYEMF 224

  Fly   248 PWLV-PFYCNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKSLKEDKN----- 306
            .||: |....| :::.|...::..|.::::..| :.....:.|.:|..||.|..:.::|.
Mouse   225 SWLLQPLPGPH-TQLQHHLGTLAAFTIQQVQKH-QGRFQTSGPARDVVDAFLLKMAQEKQDPGTE 287

  Fly   307 -VSRNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVM 370
             ..:|.::.:......|...:|..:..||..:.:.|.:...:|.|:......| |...|.|...:
Mouse   288 FTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLRYPQVQQRVREELIQELGPG-RAPSLSDRVRL 351

  Fly   371 PYTMASISEVLR-YSSSPI-VPHVAMEDTVIKGFGVRKGTIVF-INNYVLNMSESFWNHPEQFDP 432
            |||.|.:.|..| .:..|: :||.....|..:|:.:.|||.|| :...:|:....|.| |.:|.|
Mouse   352 PYTDAVLHEAQRLLALVPMGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQN-PGEFHP 415

  Fly   433 ERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGK 497
            .|||                          |.||..:..:                .|||:|:||
Mouse   416 GRFL--------------------------DEDGRLRKHE----------------AFLPYSLGK 438

  Fly   498 RTCIGQSLVRGFGFLLLANIIQNYNVNSADFSKIKLEKSSIALPKKCFKLSLRP 551
            |.|:|:.|.|...:|...:|:|.:               |:..|.....|||:|
Mouse   439 RVCLGEGLARAELWLFFTSILQAF---------------SLETPCPPGDLSLKP 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	127/522 (24%)
Cyp2s1	NP_083051.1	p450	50..487	CDD:365848	122/506 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010