DRSC/TRiP Functional Genomics Resources

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Protein Alignment spok and Cyp2c24

DIOPT Version :9

Sequence 1:NP_001104460.2 Gene:spok / 5740359 FlyBaseID:FBgn0086917 Length:553 Species:Drosophila melanogaster
Sequence 2:NP_001258283.1 Gene:Cyp2c24 / 499353 RGDID:1563697 Length:490 Species:Rattus norvegicus


Alignment Length:505 Identity:133/505 - (26%)
Similarity:224/505 - (44%) Gaps:106/505 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 PGPHPWPIIGNINLLGRFQYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKY 116
            |||.|.||||||..:.....:.  .|...:|.||.:::|..|....:||:..:.:||.|:..|:.
  Rat    31 PGPTPLPIIGNILQIDVKDISK--SFTNFSKIYGPVFTLYFGPKPTVVVHGYEAVKEALDDLGEE 93

  Fly   117 FGGRPDFFRYHKLFGGDRNNSLAL-----CDWSQLQQ------KRRNLARRHCSPRESSSYFSKM 170
            |.||..|....::     ||.|.:     ..|.:|:.      :...:.:|....|...      
  Rat    94 FSGRGSFPIVERM-----NNGLGVIFSNGTKWKELRHFSLMTLRNFGMGKRSIEDRIQE------ 147

  Fly   171 SEIGGLEVNQLLDQLTNISSGYPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIF 235
                  |.:.|:::|.. ::|..||...::..|.:|:.|..:...||:|.|:.|..::|..:|.|
  Rat   148 ------EASCLVEELRK-TNGSLCDPTFILSCAPSNVICSVVFHNRFDYKDENFLNLMEKLNENF 205

  Fly   236 WEINQGYSFDYIPWL-----VPFYCNHI----SRIVHWSASIRKFILERIVNHRESNININEPDK 291
            ..:|.       ||:     :|.:.:::    :|::...|.|:.:||.|:..|:|: ::::.| :
  Rat   206 KILNS-------PWMQVCNALPAFIDYLPGSHNRVIKNFAEIKSYILRRVKEHQET-LDMDNP-R 261

  Fly   292 DFTDALLKSLKEDKNVSRNTIIFMLED--------FIGGHSAVGNLVMLALAYIAKNPTIALHIR 348
            ||.|..|..::::|:..|..  |.:|.        |:.|.......:...|..:.|:..:...::
  Rat   262 DFIDCFLIKMEQEKHNPRTE--FTIESLMATVSDVFVAGSETTSTTLRYGLLLLLKHTEVTAKVQ 324

  Fly   349 NEVDTVSAKGIRRICLYDMNVMPYTMASISEVLRYSS--SPIVPHVAMEDTVIKGFGVRKGT-IV 410
            .|:|.|..:. ||.|:.|...||||.|.:.|:.||.:  ...|||.|..:...:.:.:.||| :|
  Rat   325 EEIDHVIGRH-RRPCMQDRTRMPYTDAMVHEIQRYINLIPNNVPHAATCNVRFRNYVIPKGTDLV 388

  Fly   411 FINNYVLNMSESFWNHPEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGK 475
            .....||:..:.|.| ||.|||..||:.|                          |:.|...|  
  Rat   389 TSLTSVLHDDKEFPN-PEVFDPGHFLDEN--------------------------GNFKKSDY-- 424

  Fly   476 QNLNNKLLKKSIPQFLPFSVGKRTCIGQSLVRGFGFLLLANIIQNYNVNS 525
                          |:|||.|||.|:|::|.|...||||..|:||:|:.|
  Rat   425 --------------FMPFSTGKRMCVGEALARMELFLLLTTIVQNFNLKS 460

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
spokNP_001104460.2 p450 52..549 CDD:299894 133/505 (26%)
Cyp2c24NP_001258283.1 p450 30..487 CDD:278495 133/505 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG45226
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X6
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

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