Protein Alignment spok and Cyp2s1

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001100965.1
• Gene: Cyp2s1 / 308445
• RGDID: 1306078
• Length: 499
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 137/531 - (25%)
• Similarity: 228/531 - (42%)
• Gaps: 101/531 - (19%)

  Fly    52 PGPHPWPIIGNINLLGRFQYNP---FYGFGTLTKKYGDIYSLSLG-HTRCIVVNNVDLIKEVLNK 112
            |||.|.|::||:     .|..|   :.||..|:||||.::::.|| ..|.:|:...|.|:|.|..
  Rat    33 PGPTPLPLLGNL-----LQLRPGALYSGFLRLSKKYGPVFTVHLGPWRRVVVLVGHDAIREALGG 92

  Fly   113 NGKYFGGRPDFFRYHKLF--------GGDRNNSLALCDWSQLQQKRRNLARRH--CSPRESSSYF 167
            ..:.|.||.......|.|        .|:|        |.|| :|...||.|.  ...||.....
  Rat    93 QAEEFSGRGTLATLDKTFDGHGVFFANGER--------WKQL-RKFTLLALRDLGMGKREGEELI 148

  Fly   168 SKMSEIGGLEVNQLLDQLTNISSGYPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFD 232
            .:       ||..|:..... :.|.|.:...|:..|::|:.|..:..:|..|.||.||.:|:...
  Rat   149 QE-------EVQNLVKAFQR-TEGRPFNPSMLLAQATSNVVCSLIFGIRLPYEDKEFQAVIQAAS 205

  Fly   233 EIFWEINQ--GYSFDYIPWLV-PFYCNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFT 294
            .....|:.  |.:::...||: |....| :::.|...::..|.::::..| :...:.:.|.:|..
  Rat   206 GTLLGISSPWGQAYEMFSWLLQPLPGPH-TQLQHHLGTLAAFTIQQVQRH-QGRSHTSGPARDVV 268

  Fly   295 DALLKSLKEDKN------VSRNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDT 353
            ||.|:.:.::|.      ..:|.::.:......|...:|..:..||..:.|.|.:...:|.|:
  Rat   269 DAFLQKMAQEKEDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLKYPQVQKRVREEL-- 331

  Fly   354 VSAKGIRRI-CLYDMNVMPYTMASISEVLR-YSSSPI-VPHVAMEDTVIKGFGVRKGTIVF-INN 414
            :...|..|. .|.|...:|||.|.:.|..| .:..|: :||...:.|..:|:.:.|||.|| :..
  Rat   332 IQELGPSRTPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTVTKTTSFRGYTLPKGTEVFPLIG 396

  Fly   415 YVLNMSESFWNHPEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLN 479
            .||:....|.| ||:|.|.|||              ||:.|   |||::
  Rat   397 SVLHDPAVFRN-PEEFHPSRFL--------------DDDGR---IRKHE---------------- 427

  Fly   480 NKLLKKSIPQFLPFSVGKRTCIGQSLVRGFGFLLLANIIQNYNVNS----ADFSKIKLEKSSIAL 540
                     .|||:|:|||.|:|:.|.|...:|...:|:|.:::::    .|.|.....:....:
  Rat   428 ---------AFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSLDTPCPPGDLSLKPAVRGLFNI 483

  Fly   541 PKKCFKLSLRP 551
            |.. |:|.:.|
  Rat   484 PPD-FQLQVWP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	136/527 (26%)
Cyp2s1	NP_001100965.1	p450	48..491	CDD:365848	128/507 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010