Protein Alignment spok and Cyp2b21

DIOPT Version :10

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_942028.1
• Gene: Cyp2b21 / 292728
• RGDID: 735174
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 141/546 - (25%)
• Similarity: 231/546 - (42%)
• Gaps: 119/546 - (21%)

  Fly     8 VLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYN 72
            :|||     :|..::.||::.:...:   |.|           .|||.|.|::||:..:.|  ..
  Rat     7 LLFA-----LLTGFLLLLIRGQGNGY---GHL-----------PPGPCPLPLLGNVLQMDR--RG 50

  Fly    73 PFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGR-------PDFFRYHKLF 130
            ....|..|..||||:.::.||....:::...:.|:|.|..:.:.|.||       |....|..:|
  Rat    51 LLKSFIQLRDKYGDVVTVHLGPRPIVMLYGTETIREALVDHAEAFSGRGTVAVVQPIIQDYGMIF 115

  Fly   131 -GGDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPC 194
             .|:|        |..|  :|.:||..........|...::.|    |...|:::|... .|.|.
  Rat   116 ANGER--------WKIL--RRFSLATMRDFGMGKRSVEERIKE----EAQCLVEELKKY-KGAPL 165

  Fly   195 DVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIF----------WEINQGYSFDYIPW 249
            |....:...:||:.|..:...||:|:|..|..:::.|.||.          :|:..|: ..|.|.
  Rat   166 DPTFHLQCITANIICSIVFGERFDYTDHQFLHLLDLFYEILSLVSSFSSQVFELFTGF-LKYFPG 229

  Fly   250 LVPFYCNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDA-LLKSLKEDKN-----VS 308
            .    ..|||:.:.   .|..||...:..|| :.::.:.| :||.|. ||:..||..|     ..
  Rat   230 T----HRHISKNIE---EILNFIGHCVEKHR-ATLDPSTP-RDFIDTYLLRMEKEKLNHHTEFHH 285

  Fly   309 RNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNV-MPY 372
            :|.::.:|..|..|.......:......:.|.|.:|..::.|:|.|.  |..|:...|..: |||
  Rat   286 QNLMMSVLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVI--GSHRVPTLDDRIKMPY 348

  Fly   373 TMASISEVLRYSS-SPI-VPHVAMEDTVIKGFGVRKGTIVF-INNYVLNMSESFWNHPEQFDPER 434
            |.|.|.|:.|:|. .|| :||...:||:.:|:.:.|...|: |.:..|: ...::.||:.|:||.
  Rat   349 TDAVIHEIQRFSDLVPIGLPHRVTKDTLFRGYLLPKNIEVYPILSSALH-DPQYFEHPDTFNPEH 412

  Fly   435 FLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRT 499
            ||:.|..                 ::||:                         .|||||.|||.
  Rat   413 FLDANGA-----------------LKKNE-------------------------AFLPFSTGKRV 435

  Fly   500 CIGQSLVRGFGFLLLANIIQNYNVNS 525
            |:|:.:.|...||....|:||::|:|
  Rat   436 CLGEGIARNELFLFFTTILQNFSVSS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	CYP1_2-like	85..547	CDD:410710	121/469 (26%)
Cyp2b21	NP_942028.1	CYP2B	62..486	CDD:410765	122/470 (26%)