Protein Alignment spok and Cyp2b3

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_775416.1
• Gene: Cyp2b3 / 286953
• RGDID: 628627
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 142/587 - (24%)
• Similarity: 251/587 - (42%)
• Gaps: 141/587 - (24%)

  Fly     1 MLTSVFYVLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINL 65
            |.|||..:|      .:|:|::..|::...|   |.|.|           .|||.|.|::||:..
  Rat     1 MDTSVLLLL------AVLLSFLLFLVRGHAK---VHGHL-----------PPGPRPLPLLGNLLQ 45

  Fly    66 LGRFQYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGR-------PDF 123
            :.|..:..  .|..|.:|:||::::..|....:::.....|:|.|..:.:.|.||       |..
  Rat    46 MDRGGFRK--SFIQLQEKHGDVFTVYFGPRPVVMLCGTQTIREALVDHAEAFSGRGIIAVLQPIM 108

  Fly   124 FRYHKLFGGDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIG----------GLEV 178
            ..|...|               :.::|..:.||        .:.:.|.:.|          ..|.
  Rat   109 QEYGVSF---------------VNEERWKILRR--------LFVATMRDFGIGKQSVEDQIKEEA 150

  Fly   179 NQLLDQLTNISSGYPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEIN---- 239
            ..|:::|.| ..|...|...|....:.|:.|..:...||:|.|:.|.::::.....|..|:
  Rat   151 KCLVEELKN-HQGVSLDPTFLFQCVTGNIICSIVFGERFDYRDRQFLRLLDLLYRTFSLISSFSS 214

  Fly   240 ---QGYSFDYIPWLVPFYCNHISRIVHWS-ASIRKFILERIVNHRESNININEPDKDFTDALLKS 300
               :.|| |::.     |...:.|.::.: ..:..:|...:.||| :.::.|.| :||.|..|..
  Rat   215 QMFEVYS-DFLK-----YFPGVHREIYKNLKEVLDYIDHSVENHR-ATLDPNAP-RDFIDTFLLH 271

  Fly   301 LKEDK--NVSR----NTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGI 359
            ::::|  :.:.    |.:|.:|..|:.|..:..|.:......:.|.|.:|..::.|:|.|.  |.
  Rat   272 MEKEKLNHYTEFHHWNLMISVLFLFLAGTESTSNTLCYGFLLMLKYPHVAEKVQKEIDQVI--GS 334

  Fly   360 RRI-CLYDMNVMPYTMASISEVLRYSS-SPI-VPHVAMEDTVIKGFGVRKGT-IVFINNYVLNMS 420
            :|: .|.|.:.||||.|.|.|:.|:|. ||: :|....:||:.:|:.:.|.| :.||.:..|: .
  Rat   335 QRVPTLDDRSKMPYTEAVIHEIQRFSDVSPMGLPCRITKDTLFRGYLLPKNTEVYFILSSALH-D 398

  Fly   421 ESFWNHPEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKK 485
            ..::..|:.|:||.||:.|....     ||:
  Rat   399 PQYFEQPDTFNPEHFLDANGALK-----KCE---------------------------------- 424

  Fly   486 SIPQFLPFSVGKRTCIGQSLVRGFGFLLLANIIQNYNVNS-ADFSKIKL--EKSSIA----LPKK 543
               .|:|||:|||.|:|:.:.|...||....|:|||:|:| .|.:.|.:  ::|.:|    :.|.
  Rat   425 ---AFMPFSIGKRMCLGEGIARSELFLFFTTILQNYSVSSPVDPNTIDMTPKESGLAKVAPVYKI 486

  Fly   544 CF 545
            ||
  Rat   487 CF 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	130/536 (24%)
Cyp2b3	NP_775416.1	p450	42..488	CDD:278495	122/524 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010