Protein Alignment spok and Cyp2r1

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_796356.2
• Gene: Cyp2r1 / 244209
• MGIID: 2449771
• Length: 501
• Species: Mus musculus
• Alignment Length: 543
• Identity: 142/543 - (26%)
• Similarity: 231/543 - (42%)
• Gaps: 112/543 - (20%)

  Fly    11 AIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYNPFY 75
            |:|..::|:.:|           :|:..|.::::...|  .|||...|.:|||..|......|..
Mouse    13 ALAGALLLLLFV-----------LVVRQLLRQRRPAGF--PPGPPRLPFVGNICSLALSADLPHV 64

  Fly    76 GFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKL--FGGDRNNSL 138
            .....::.||:|:||.||....:|:|..|::||.|....:.|..||....:.|:  .||..|:..
Mouse    65 YMRKQSRVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRY 129

  Fly   139 ALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPCDVKPLILAA 203
            .. .|  :..:|..:...|.......|:.||:.|    |...|:|.:.....| |.|:|.||..|
Mouse   130 GR-GW--IDHRRLAVNSFHYFGSGQKSFESKILE----ETWSLIDAIETYKGG-PFDLKQLITNA 186

  Fly   204 SANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQG---YSFDYIPW--LVPF---------- 253
            .:|:....:...||.|.|..||.:||.|.|.. |:...   :.::..||  ::||
Mouse   187 VSNITNLILFGERFTYEDTDFQHMIELFSENV-ELAASAPVFLYNAFPWIGILPFGKHQRLFRNA 250

  Fly   254 --YCNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKSLKEDKN-----VSRNT 311
              ..:.:||::..:|..||   ..:.:|             |.||.|..:.:.:|     .|:..
Mouse   251 DVVYDFLSRLIEKAAVNRK---PHLPHH-------------FVDAYLDEMDQGQNDPLSTFSKEN 299

  Fly   312 IIFML-EDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPYTMA 375
            :||.: |..|.|.....|::..|:.::|..|.|...:..|:|.:.....|....|... ||||.|
Mouse   300 LIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVHKEIDLIVGHNRRPSWEYKCK-MPYTEA 363

  Fly   376 SISEVLRYSSSPIVP----HVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPERFL 436
            .:.||||:.:  |||    |...||.|::|:.:.|||.|..|.|.::..|.:|..|:.|.|||||
Mouse   364 VLHEVLRFCN--IVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFL 426

  Fly   437 ENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRTCI 501
            ::|....|:..|                                          :|||:|:|.|:
Mouse   427 DSNGYFTKKEAL------------------------------------------IPFSLGRRHCL 449

  Fly   502 GQSLVRGFGFLLLANIIQNYNVN 524
            |:.|.|...||...:::|.::::
Mouse   450 GEQLARMEMFLFFTSLLQQFHLH 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	135/502 (27%)
Cyp2r1	NP_796356.2	p450	40..497	CDD:278495	135/503 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920