Protein Alignment spok and Cyp2d3

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_775116.1
• Gene: Cyp2d3 / 24303
• RGDID: 2472
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 120/525 - (22%)
• Similarity: 226/525 - (43%)
• Gaps: 90/525 - (17%)

  Fly    18 LISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYNPFYGFGTLTK 82
            :.:.:|:||         :.|:::.:::.. ...|||.|||::|  |||.....|..|....|..
  Rat    14 IFTVIFILL---------VDLMHRRQRWTS-RYPPGPVPWPVLG--NLLQVDLCNMPYSMYKLQN 66

  Fly    83 KYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKLFGGDRNNSLALC----DW 143
            :|||::||.:|....:|:|.:..::|:|...|:....||:...:..:..|.:...:.|.    :|
  Rat    67 RYGDVFSLQMGWKPVVVINGLKAVQELLVTCGEDTADRPEMPIFQHIGYGHKAKGVVLAPYGPEW 131

  Fly   144 SQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPCDVKPLILAASANMF 208
            .  :|:|.:::..........|....:::    |.:.|.|.|| ..:|.|.|...|:..|..|:.
  Rat   132 R--EQRRFSVSTLRNFGVGKKSLEQWVTD----EASHLCDALT-AEAGRPLDPYTLLNKAVCNVI 189

  Fly   209 CQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGYSFDYIPWLVPFYCNHISRIVHWSASI----R 269
            ...:.:.||:|.|..|.|:::...|...|  |...|..:..:.|.    :.||...:..:    :
  Rat   190 ASLIYARRFDYGDPDFIKVLKILKESMGE--QTGLFPEVLNMFPV----LLRIPGLADKVFPGQK 248

  Fly   270 KFI--LERIVNHRESNININEPDKDFTDALLKSLKEDKNVSRNT-----IIFMLEDFIGGHSAVG 327
            .|:  ::.:|...:...:.::|.:|.|||.|..:::.|....::     :..::.|..|......
  Rat   249 TFLTMVDNLVTEHKKTWDPDQPPRDLTDAFLAEIEKAKGNPESSFNDANLRLVVNDLFGAGMVTT 313

  Fly   328 NLVML-ALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPYTMASISEVLRYSS-SPI-V 389
            ::.:. ||..:..:|.:...::.|:|.|..: :|...:.|...||:|.|.|.||.|::. .|: :
  Rat   314 SITLTWALLLMILHPDVQCRVQQEIDEVIGQ-VRHPEMADQAHMPFTNAVIHEVQRFADIVPMNL 377

  Fly   390 PHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPERFL--ENNFTNNKESGLKCDD 452
            ||....|..::||.:.|||.:..|...:...|:.|..|.:|.||.||  :.||..::
  Rat   378 PHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHE-------- 434

  Fly   453 NKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRTCIGQSLVRGFGFLLLANI 517
                                                .|:|||.|:|.|:|:.|.|...||....:
  Rat   435 ------------------------------------AFMPFSAGRRACLGEPLARMELFLFFTCL 463

  Fly   518 IQNYN 522
            :|.::
  Rat   464 LQRFS 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	116/491 (24%)
Cyp2d3	NP_775116.1	p450	37..496	CDD:278495	116/492 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920