Protein Alignment spok and Cyp2c23

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_017173651.1
• Gene: Cyp2c23 / 226143
• MGIID: 1888897
• Length: 501
• Species: Mus musculus
• Alignment Length: 537
• Identity: 134/537 - (24%)
• Similarity: 223/537 - (41%)
• Gaps: 106/537 - (19%)

  Fly    52 PGPHPWPIIGNINLLGRFQYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKY 116
            |||.|.||||||..|.......  ....|.|:||.:|:|..|....:|::..|::||.|...|..
Mouse    35 PGPTPLPIIGNILQLDLKDIPA--SLSKLAKEYGPVYTLYFGSWPTVVLHGYDVVKEALLNQGDE 97

  Fly   117 FGGR------PDFFRYHKLFGGDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGG 175
            |.||      .|..:.|.:...:......|..:|.:..|...:.:|....|...
Mouse    98 FLGRGPLPIIEDSQKGHGIVFSEGERWKLLRRFSLMTLKNFGMGKRSLEERVQE----------- 151

  Fly   176 LEVNQLLDQLTNISSGYPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQ 240
             |...|:::| :.:...|.|...::..|..|:.|..:.:.||.|:||.|..:::..::.|:::|.
Mouse   152 -EARCLVEEL-HKTEAQPFDPTFILACAPCNVICSILFNERFPYNDKTFLNLMDLLNKNFYQLNS 214

  Fly   241 GYSFDYIPW-----LVPFYCNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKS 300
            .:...|..|     .:|......|:.:   ..::.||||::..|:||....|  .:|:.|..|..
Mouse   215 IWIQMYNLWPTIMKYIPGKHREFSKRL---GGVKNFILEKVKEHQESLDPAN--PRDYIDCFLSK 274

  Fly   301 LKEDKNVSRNTIIFMLED--------FIGGHSAVGNLVMLALAYIAKNPTI-------ALHIRNE 350
            ::|:|:..::.  |.||:        |..|.......:...|..:.|:|.:       ...:..|
Mouse   275 IEEEKHNLKSD--FNLENLAICGSNLFTAGTETTSTTLRFGLLLLVKHPEVQGTPSEEGAKVHEE 337

  Fly   351 VDTVSAKGIRRICLYDMNVMPYTMASISEVLRY----SSSPIVPHVAMEDTVIKGFGVRKGTIV- 410
            :|.|..:. :...:.|...:|||.|.:.|:.||    .||  :||..::||..:.:.:.|||.|
Mouse   338 LDRVIGRH-QPPSMKDKMKLPYTDAVLHEIQRYITLLPSS--LPHAVVQDTKFRHYVIPKGTAVF 399

  Fly   411 -FINNYVLNMSESFWNHPEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYG 474
             |:::.:|:..|  :.:||:|||..||:.|                          |..|...|
Mouse   400 PFLSSILLDQKE--FPNPEKFDPGHFLDKN--------------------------GCFKKTDY- 435

  Fly   475 KQNLNNKLLKKSIPQFLPFSVGKRTCIGQSLVRGFGFLLLANIIQNYN----VNSADFSKIKLEK 535
                           |:|||:|||:|:|:.|.|...||....|:|.::    |...|.....:..
Mouse   436 ---------------FVPFSLGKRSCVGEGLARMELFLFFTTILQKFSLKALVEPKDLDIKPVTT 485

  Fly   536 SSIALPKKCFKLSLRPR 552
            ....||.. :||.|.||
Mouse   486 GLFNLPPP-YKLRLVPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	131/532 (25%)
Cyp2c23	XP_017173651.1	p450	34..496	CDD:365848	129/530 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010