Protein Alignment spok and cyp-36A1

DIOPT Version :10

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_492267.1
• Gene: cyp-36A1 / 183193
• WormBaseID: WBGene00007913
• Length: 493
• Species: Caenorhabditis elegans
• Alignment Length: 582
• Identity: 134/582 - (23%)
• Similarity: 239/582 - (41%)
• Gaps: 145/582 - (24%)

  Fly     8 VLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGN--------IN 64
            :|||..:.:::|..:||   |: .|..:.||            .|||.|||.|||        |:
 Worm     1 MLFAQLVILVIIVMLFL---CR-FANKLRGL------------PPGPTPWPFIGNTFQVPEDRID 49

  Fly    65 LLGRFQYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKL 129
            |:    .|.|      .||||.|::|.|... .||:.:.|::|..:.|||:.|.||||.|....|
 Worm    50 LI----INEF------KKKYGGIFTLWLPFP-TIVICDYDMLKRNIVKNGESFSGRPDTFIMDML 103

  Fly   130 FGGDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIG--GLEVNQLLDQLTNISSGY 192
            ..|:........:|.:.|             |..:::..:...:|  |.:     |.:.:::||.
 Worm   104 VQGNYGLFFMENNWWKAQ-------------RRFTTHIFRSLGVGQAGTQ-----DTIASLASGL 150

  Fly   193 ----------PCDVKPLILAASANMFCQYMCSVRFNYSDK-------GFQKIIEYFDEIFWEINQ 240
                      |.:::||::....|:..:::......:::.       ....::|:|.....::
 Worm   151 VEKIDGQKDKPIELRPLLVHVVGNVIHKHLFGFTREWNETEILDFHVAINDVLEHFTSPKTQL-- 213

  Fly   241 GYSFDYIPWLVPFYCNH-----ISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKS 300
               .|..|||.  |.:.     |.|....:.:|.:.:.:.:..|: :.||.:|....:.||.||.
 Worm   214 ---LDAWPWLA--YLDKPLSLGIPRTTRANDAIIQNLEQALAKHK-TGINYDEEPSSYMDAFLKE 272

  Fly   301 LK--------EDKNVSRNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAK 357
            :|        ||....:..|:.:.:.:..|...:..::..|..|:..||.....|..|:|....:
 Worm   273 MKIRAAENALEDGFTEKQLIVAIYDLYSAGMETIIIVLRFAFLYLVNNPETQKRIHEELDRNVGR 337

  Fly   358 GIRRICLYDMNVMPYTMASISEVLRYSSSPIVPHVAMEDTV-----IKGFGVRKGTIVFINNYVL 417
            . |::.:.|...:|||.|.:.||  |....::|...:..|:     .:|:.:..||.|......:
 Worm   338 E-RQVVMDDQKHLPYTCAFLQEV--YRLGYVLPVNFLRCTLTDVEDCEGYRLNAGTRVIAQFQSV 399

  Fly   418 NMSESFWNHPEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKL 482
            ::.:..:..||.|:|:|||                |.|.|:||.:              .:|
 Worm   400 HVDKKHFPDPEHFNPDRFL----------------NSRGEYIRDD--------------RVN--- 431

  Fly   483 LKKSIPQFLPFSVGKRTCIGQSLVRGFGFLLLANIIQNY--NVNSADFSKIKLEKSSIALPK 542
                     |||:|||:|:|::|.|...||....::||:  :.:......|.:..||:..||
 Worm   432 ---------PFSMGKRSCLGENLARMEVFLYFCTLMQNFEWHTDGPYAPPIDVITSSLRAPK 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	CYP1_2-like	85..547	CDD:410710	108/497 (22%)
cyp-36A1	NP_492267.1	CYP1_2-like	60..488	CDD:410710	108/497 (22%)