Protein Alignment spok and CYP2F1

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_016881873.1
• Gene: CYP2F1 / 1572
• HGNCID: 2632
• Length: 573
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 129/510 - (25%)
• Similarity: 209/510 - (40%)
• Gaps: 108/510 - (21%)

  Fly    13 AITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQA---PGPHPWPIIGNINLLGRFQYNPF 74
            ||.::|::.|.|||....:                 |:.   |||.|..|:||:.||  ...:..
Human    82 AILLLLLALVCLLLTLSSR-----------------DKGKLPPGPRPLSILGNLLLL--CSQDML 127

  Fly    75 YGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGR---PDFFRYHKLFG----- 131
            .....|:|:||.:|::.||..|.:|::....:||.|...|:.|.||   |.||.:.|..|
Human   128 TSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSS 192

  Fly   132 GDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPCDV 196
            |||        |..|:|....:.|.....:.|..  .::.|.|..    ||.:|.. :.|.|.|.
Human   193 GDR--------WKVLRQFSIQILRNFGMGKRSIE--ERILEEGSF----LLAELRK-TEGEPFDP 242

  Fly   197 KPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIF------WEINQGYSFDYIPWLVPFYC 255
            ..::..:.:|:.|..:...||:|.|:....||...::.|      |    |..:|..|.|:.:..
Human   243 TFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPW----GELYDIFPSLLDWVP 303

  Fly   256 NHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKSLKEDK-----NVSRNTIIFM 315
            ....||......:|..|...:.:| :::::...| :||....|..:.|:|     :...:|::..
Human   304 GPHQRIFQNFKCLRDLIAHSVHDH-QASLDPRSP-RDFIQCFLTKMAEEKEDPLSHFHMDTLLMT 366

  Fly   316 LEDFI-GGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPYTMASISE 379
            ..:.: ||...|...:..|...:.|.|.:...::.|:|.|..:. |...|.|...||||.|.|.|
Human   367 THNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRA-RLPALKDRAAMPYTDAVIHE 430

  Fly   380 VLRYSS-SPI-VPHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPERFLENNFTN 442
            |.|::. .|: :||....||..:||.:.|||.|......::...|.:..|::|:||.||:
Human   431 VQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLD----- 490

  Fly   443 NKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGK 497
                                                .|:..||| |.|:|||.|:
Human   491 ------------------------------------ANQSFKKS-PAFMPFSAGE 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	121/468 (26%)
CYP2F1	XP_016881873.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920