Protein Alignment spok and Cyp2f2

DIOPT Version :10

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_031843.2
• Gene: Cyp2f2 / 13107
• MGIID: 88608
• Length: 491
• Species: Mus musculus
• Alignment Length: 577
• Identity: 149/577 - (25%)
• Similarity: 241/577 - (41%)
• Gaps: 129/577 - (22%)

  Fly    13 AITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYNPFYGF 77
            ||.::|::.:.|.|....:.           |.|.   .|||.|.||:|  |||.....:.....
Mouse     7 AILLLLLAVISLSLTFSSRG-----------KGQL---PPGPKPLPILG--NLLQLRSQDLLTSL 55

  Fly    78 GTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGR---PDFFRYHKLFGGDRNNSLA 139
            ..|:|:||.::::.||....||::....:||.|...|:.|.||   |.||.:      .|.|.:|
Mouse    56 TKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNF------TRGNGIA 114

  Fly   140 LCD---WSQLQ----QKRRN--LARRHCSPR--ESSSYFSKMSEIGGLEVNQLLDQLTNISSGYP 193
            ..|   |..|:    |..||  :.:|....|  |..|:.        |||.:.::       |.|
Mouse   115 FSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFL--------LEVLRKME-------GKP 164

  Fly   194 CDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGYSFDYIPWLVPFYCNHI 258
            .|...::..:.:|:.|..:...||:|.|:....||.:       ||..:.....||...:  |..
Mouse   165 FDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHF-------INDNFKIMSSPWGEMY--NIF 220

  Fly   259 SRIVHW-----SASIRKF-----ILERIVNHRESNININEPDKDFTDALLKSLKEDK-----NVS 308
            ..::.|     ....|.|     ::.|.|...:.:::.|.| :||.|..|..:.::|     :.:
Mouse   221 PSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMAQEKQDPLSHFN 284

  Fly   309 RNTIIFMLEDFI-GGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPY 372
            .:|::....:.: ||...||..:..|...:.|.|.:...::.|:|.|..:. |...|.|...|||
Mouse   285 MDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRS-RMPTLEDRTSMPY 348

  Fly   373 TMASISEVLRYSS-SPI-VPHVAMEDTVIKGFGVRKGT-IVFINNYVLNMSESFWNHPEQFDPER 434
            |.|.|.||.|::. .|: :||....||..:||.:.||| ::.:.|.|...|:.| ..|::|:||.
Mouse   349 TDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQF-KTPQEFNPEH 412

  Fly   435 FLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRT 499
            ||::|.:                                         .||| |.|:|||.|:|.
Mouse   413 FLDDNHS-----------------------------------------FKKS-PAFMPFSAGRRL 435

  Fly   500 CIGQSLVRGFGFLLLANIIQNYN----VNSADFSKIKLEKSSIALPKKCFKLSLRPR 552
            |:|:.|.|...|:...:|:||:.    |:..|.....|......||:. |:|.:..|
Mouse   436 CLGEPLARMELFIYFTSILQNFTLQPLVDPEDIDLTPLSSGLGNLPRP-FQLCMHIR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	CYP1_2-like	85..547	CDD:410710	127/498 (26%)
Cyp2f2	NP_031843.2	Cyp2F	62..486	CDD:410762	128/499 (26%)