Protein Alignment spok and Cyp2c38

DIOPT Version :10

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_034132.2
• Gene: Cyp2c38 / 13097
• MGIID: 1306819
• Length: 490
• Species: Mus musculus
• Alignment Length: 566
• Identity: 143/566 - (25%)
• Similarity: 235/566 - (41%)
• Gaps: 119/566 - (21%)

  Fly    18 LISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQYNPFYGFGTLTK 82
            |::::.|.|    .:.:::.|..|..:....  .|||.|:|||||...:....:|  ......:|
Mouse     3 LVTFLVLTL----SSLILLSLWRQRSRRGRL--PPGPTPFPIIGNFLQIDVKNFN--QSLTNFSK 59

  Fly    83 KYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKLFGGDRNNSLALC-----D 142
            .||.:::|.||....:|::..:.:||.|..:|:.|.||.:.....|:     ||.|.:.     .
Mouse    60 TYGPVFTLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKI-----NNGLGITFSNGNS 119

  Fly   143 WSQLQQ----KRRNL--ARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSGYPCDVKPLIL 201
            |.:.::    ..|||  .:|:...|...            |...|:::|.. :.|.|||...::.
Mouse   120 WKETRRFTLMTLRNLGMGKRNIEDRVRE------------EAQCLVEELRK-TKGSPCDPTFILS 171

  Fly   202 AASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGYSFDYIPWLVPFYCNHISRIVHWSA 266
            .|..|:.|..:...||:|.||.|..:::       ::|:.......|||.  .||:...::.:..
Mouse   172 CAPCNVICSIIFQDRFDYKDKDFLMLMK-------KLNENVKILSSPWLQ--VCNNFPLLIDYCP 227

  Fly   267 S-----------IRKFILERIVNHRESNININEPDKDFTDALLKSLKEDKNVSR------NTIIF 314
            .           ||.::||::..|:|| :::..| :||.|..|...|:..::.:      |.:..
Mouse   228 GSHHKVLKNFKYIRSYLLEKVKEHQES-LDVTNP-RDFIDYFLIKQKQANHIEQAEYSLENLVCT 290

  Fly   315 MLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPYTMASISE 379
            :...|..|.......:..||..:.|.|.:...::.|:|.|..:. |..|:.|.:.||||.|.|.|
Mouse   291 INNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRH-RSPCMQDRSRMPYTDAMIHE 354

  Fly   380 VLRYSS--SPIVPHVAMEDTVIKGFGVRKGTIVFIN-NYVLNMSESFWNHPEQFDPERFLENNFT 441
            |.|:.:  ...:||....|...:.:.:.|||.|..: ..||:.|:.|.| ||.|||..||:.|
Mouse   355 VQRFINLVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPN-PEMFDPGHFLDAN-- 416

  Fly   442 NNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRTCIGQSLV 506
                                    |:.|...|                |:.||.|||.|.|:.|.
Mouse   417 ------------------------GNFKKSDY----------------FMTFSAGKRVCAGEGLA 441

  Fly   507 RGFGFLLLANIIQNYNVNS----ADFSKIKLEKSSIALP---KKCF 545
            |...||:|..|:||:.:.|    .|...|......|.||   :.||
Mouse   442 RMELFLILTTILQNFKLKSLVHPKDIDMIPFVNGLITLPPHYQLCF 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	CYP1_2-like	85..547	CDD:410710	126/499 (25%)
Cyp2c38	NP_034132.2	CYP2C-like	61..485	CDD:410758	125/496 (25%)