Protein Alignment spok and Cyp2b10

DIOPT Version :10

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_034129.1
• Gene: Cyp2b10 / 13088
• MGIID: 88598
• Length: 491
• Species: Mus musculus
• Alignment Length: 541
• Identity: 143/541 - (26%)
• Similarity: 235/541 - (43%)
• Gaps: 107/541 - (19%)

  Fly     8 VLFAIAITIILISYVFLLLKCKQKA---FVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRF 69
            ||..:|   :|:.::.||.:...|:   |                 .|||.|.|::|  |||...
Mouse     5 VLLLLA---LLVGFLLLLARGHPKSRGNF-----------------PPGPRPLPLLG--NLLQMD 47

  Fly    70 QYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGR-------PDFFRYH 127
            :......|..|.:||||::::.||....:::...|.|:|.|....:.|.||       |.|..|.
Mouse    48 RGGLLKSFIQLREKYGDVFTVHLGPRPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPTFKEYG 112

  Fly   128 KLF-GGDRNNSLALCDWSQLQQKRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSG 191
            .:| .|:|        |..|  :|.:||..........|...::.|    |...|:::|.. |.|
Mouse   113 VIFANGER--------WKTL--RRFSLATMRDFGMGKRSVEERIQE----EAQCLVEELRK-SQG 162

  Fly   192 YPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGYS--FDYIPWLVPFY 254
            .|.|...|....:||:.|..:...||.|:|:.|.:::|.|.:.|..|:...|  |:.....:.::
Mouse   163 APLDPTFLFQCITANIICSIVFGERFEYTDRQFLRLLELFYQTFSLISSFSSQMFELFSGFLKYF 227

  Fly   255 CNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKSLKEDKNVS------RNTII 313
            .....:|......:..:|...:..|| :.::.:.| :||.|..|..::::|:..      :|.::
Mouse   228 PGAHRQISKNLQELLDYIGHSVEKHR-ATLDPSVP-RDFIDIYLLRMEKEKSNQHTEFHHQNLMM 290

  Fly   314 FMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRI-CLYDMNVMPYTMASI 377
            .:|..|..|.......:......:.|.|.:|..::.|:|.|.  |..|: .|.|...||||.|.|
Mouse   291 SVLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVI--GSHRLPTLDDRTKMPYTDAVI 353

  Fly   378 SEVLRYSS-SPI-VPHVAMEDTVIKGFGVRKGTIVF-INNYVLNMSESFWNHPEQFDPERFLENN 439
            .|:.|:|. .|| |||...:||:.:|:.:.|.|.|: |.:..|: ...::..|:.|:|:.||:.|
Mouse   354 HEIQRFSDLIPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALH-DPQYFEQPDSFNPDHFLDAN 417

  Fly   440 FTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKRTCIGQS 504
                                      |:               |||| ..|||||.|||.|:|:|
Mouse   418 --------------------------GA---------------LKKS-EAFLPFSTGKRICLGES 440

  Fly   505 LVRGFGFLLLANIIQNYNVNS 525
            :.|...||...:|:||::|.|
Mouse   441 IARNELFLFFTSILQNFSVAS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	CYP1_2-like	85..547	CDD:410710	122/461 (26%)
Cyp2b10	NP_034129.1	CYP2B	62..486	CDD:410765	123/462 (27%)