Protein Alignment spok and Cyp2a4

DIOPT Version :9

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_034127.2
• Gene: Cyp2a4 / 13086
• MGIID: 88596
• Length: 494
• Species: Mus musculus
• Alignment Length: 565
• Identity: 133/565 - (23%)
• Similarity: 223/565 - (39%)
• Gaps: 141/565 - (24%)

  Fly     1 MLTSVFYVLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINL 65
            ||||...::.|:|...:|:    |:...||:.  :.|.|           .|||.|.|.:||...
Mouse     1 MLTSGLLLVAAVAFLSVLV----LMSVWKQRK--LSGKL-----------PPGPTPLPFVGNFLQ 48

  Fly    66 LGRFQ-YNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKL 129
            |...| ||...   .::::||.::::.||..|.:|:...:.:||.|....:.|.||.:...:..|
Mouse    49 LNTEQMYNSLM---KISQRYGPVFTIYLGSRRIVVLCGQETVKEALVDQAEEFSGRGEQATFDWL 110

  Fly   130 FGGDRNNSLALCDWSQLQQKRR---------NLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQL 185
            |.|   ..:|.....:.:|.||         .:.:|....|        :.|..|.    |:|..
Mouse   111 FKG---YGIAFSSGERAKQLRRFSITTLRDFGVGKRGIEER--------IQEEAGF----LIDSF 160

  Fly   186 TNISSGYPCDVKPLILAAS--ANMFCQYMCSVRFNYSDKGFQKIIEYFDEIFWEINQGYSFDYIP 248
            ...:..:   :.|....:.  :|:....:...||:|.||.|..::.                .:.
Mouse   161 RKTNGAF---IDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLR----------------MML 206

  Fly   249 WLVPFYCNHISRIVHWSASIRK------------------FILERIVNHRESNININEPDKDFTD 295
            ..:.|....:.::....:|:.|                  ||.:: |.|.:..::.|.| :||.|
Mouse   207 GSLQFTATSMGQVYEMFSSVMKHLPGPQQQAFKELQGLEDFITKK-VEHNQRTLDPNSP-RDFID 269

  Fly   296 A-LLKSLKEDKNVS-----RNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTV 354
            : |::.|:|.||.:     :|.::..|..|..|...|...:......:.|.|.|...:..|:|.|
Mouse   270 SFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKYPDIEAKVHEEIDRV 334

  Fly   355 SAKGIRRICLYDMNVMPYTMASISEVLRYSSSPIVP----HVAMEDTVIKGFGVRKGTIVFINNY 415
            ..:. |:....|...||||.|.|.|:.|::.  ::|    ....:||..:.|.:.|||.||....
Mouse   335 IGRN-RQPKYEDRMKMPYTEAVIHEIQRFAD--LIPMGLARRVTKDTKFRDFLLPKGTEVFPMLG 396

  Fly   416 VLNMSESFWNHPEQFDPERFLENNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNN 480
            .:.....|:::|:.|:|:.||                          |:.|.
Mouse   397 SVLKDPKFFSNPKDFNPKHFL--------------------------DDKGQ------------- 422

  Fly   481 KLLKKSIPQFLPFSVGKRTCIGQSLVRGFGFLLLANIIQNYNVNS 525
              .||| ..|:|||:|||.|.|:.|.|...||.|.||:||::..|
Mouse   423 --FKKS-DAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKS 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	p450	52..549	CDD:299894	121/514 (24%)
Cyp2a4	NP_034127.2	p450	34..491	CDD:278495	121/515 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010