Protein Alignment spok and cyp2a6.13

DIOPT Version :10

• Sequence 1: NP_001104460.2
• Gene: spok / 5740359
• FlyBaseID: FBgn0086917
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_031746917.1
• Gene: cyp2a6.13 / 116406634
• XenbaseID: XB-GENE-956774
• Length: 500
• Species: Xenopus tropicalis
• Alignment Length: 574
• Identity: 135/574 - (23%)
• Similarity: 232/574 - (40%)
• Gaps: 132/574 - (22%)

  Fly     9 LFAI-AITIILIS--YVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPIIGNINLLGRFQ 70
            :|.: :.|::|:|  .:::.|..|||.                :..|||...||.||::.|.  .
 Frog    11 MFGVNSYTLVLVSICLIYMYLLHKQKG----------------NLPPGPQGLPIWGNLHQLD--T 57

  Fly    71 YNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGRPDFFRYHKLFGGDRN 135
            .:.....|.::|.||.::::.||....:|:.....:||.|.:....|.||.:|...|:...|
 Frog    58 KDLVKSLGDMSKIYGPVFTIHLGPKPNVVLYGYKAVKEALVEQADIFSGRGEFKVVHRFTKG--- 119

  Fly   136 NSLALCD---WSQLQQ------KRRNLARRHCSPRESSSYFSKMSEIGGLEVNQLLDQLTNISSG 191
            |.|...:   |..|::      :...:.:|....|..             |..|.|.:....::.
 Frog   120 NGLVFSNGEKWKTLRRFALTTLRNFGMGKRGVEERIK-------------EEAQFLMEAFKHTNQ 171

  Fly   192 YPCDVKPLILAASANMFCQYMCSVRFNYSDKGFQKIIEYFDEIF------WEINQGYSFDYIPWL 250
            .|.|....:..|.:|:.|..:...||:|.||.|..::...:|.|      |    |..::..|.:
 Frog   172 NPFDPTFFLSRAVSNVICSIVFGDRFDYGDKRFLMLLSLINESFQLMSSQW----GMFYNIFPGV 232

  Fly   251 VPFYCNHISRIVHWSASIRKFILERIVNHRESNININEPDKDFTDALLKSLKED--KNVSR---N 310
            :.:.....::|......|:.|:||.:..|.|: ...:.| :|..|..|..:|::  |.:|.   .
 Frog   233 MKYLPGPHNQIFQNFEKIKLFLLEMLKRHEET-FQQDSP-RDLMDCFLLEIKKENGKPLSHFNIE 295

  Fly   311 TII---FMLEDFIGGHSAVGNLVMLALAYIAKNPTIALHIRNEVDTVSAKGIRRICLYDMNVMPY 372
            |::   |.|  |.||...|...:...:..:.|...|...|:.|:|||..|. |...:.|.:.|||
 Frog   296 TLVMTSFTL--FFGGTETVSTTLRYGILILMKYTNITEKIQEEIDTVIGKD-RFPTMDDRSRMPY 357

  Fly   373 TMASISEVLRYSS-SPI-VPHVAMEDTVIKGFGVRKGTIVFINNYVLNMSESFWNHPEQFDPERF 435
            |.|.|.|:.|::| .|: :||...:||..:|:.:.|||.|......::...:.:..|:.|:|..|
 Frog   358 TDAVIHEIQRFASIIPLSLPHSVTQDTYFRGYKLPKGTNVIPVLSSVHTDPTKYKEPQGFNPHNF 422

  Fly   436 LE--NNFTNNKESGLKCDDNKRTEFIRKNDNDGSTKSKKYGKQNLNNKLLKKSIPQFLPFSVGKR 498
            |:  |.|.||:                                            .|:|||.|||
 Frog   423 LDENNQFKNNE--------------------------------------------AFMPFSSGKR 443

  Fly   499 TCIGQSLVRGFGFLLLANIIQNYNVNSADFSKIKLEKSSIALPKKCFKLSLRPR 552
            .|||:||.|...|:..:.::||:.:......:               ::.|:||
 Frog   444 ICIGESLARMELFIFFSTLLQNFTLQPTQNPE---------------RIDLKPR 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spok	NP_001104460.2	CYP1_2-like	85..547	CDD:410710	113/488 (23%)
cyp2a6.13	XP_031746917.1	cytochrome_P450	71..495	CDD:477761	117/496 (24%)