Protein Alignment CG34357 and Adcy7

DIOPT Version :10

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: NP_445848.1
• Gene: Adcy7 / 84420
• RGDID: 619966
• Length: 1100
• Species: Rattus norvegicus
• Alignment Length: 281
• Identity: 84/281 - (29%)
• Similarity: 141/281 - (50%)
• Gaps: 49/281 - (17%)

  Fly  1071 QLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSD-------------------VTIYFSDI 1116
            :|.:|:::.|.||..:||:.::..:|:.:....:|..|                   |:|.::||
  Rat   223 KLRVEKRQQENLLLSVLPAHISMGMKLAIIERLKEGGDRHYTPDNNFHSLYVKRHQNVSILYADI 287

  Fly  1117 VGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIPDHAEQIATM 1181
            ||||.:|:.|||.::|.:||:|:..||....|....:::.:||.|..||||||.:|.||.....|
  Rat   288 VGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKM 352

  Fly  1182 ALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWR 1246
            .||:.....:  |:...||.:.:|:|:|:|....||:||...:|.::...|:.|:|||:.|...|
  Rat   353 GLDICEAIKQ--VREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGR 415

  Fly  1247 IHMSQETRDRLDARGGYAIEPRGLIDIKGKG--------MMN--TFWLLGKKGFDKPLPAPPPIG 1301
            :|:::.|.:.||.  .|.:|       .|.|        .||  |:.::..:....|||
  Rat   416 VHITEATLNHLDK--AYEVE-------DGHGEQRDPYLKEMNIRTYLVIDPRSQQPPLP------ 465

  Fly  1302 ESHGLDESLIRNSITLKAQAN 1322
             ||.|.:.  :...|||.:|:
  Rat   466 -SHHLSKP--KGDATLKMRAS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	Protein Kinases, catalytic domain	763..1041	CDD:473864
		HNOBA	<1047..1095	CDD:462234	7/23 (30%)
		CYCc	1074..1266	CDD:214485	67/210 (32%)
Adcy7	NP_445848.1	AcyC	48..461	CDD:441717	74/248 (30%)
		Guanylate_cyc	272..422	CDD:425528	54/151 (36%)
		Adcy_cons_dom	487..594	CDD:461877
		Guanylate_cyc	891..1087	CDD:425528