DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34357 and adcy6a

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	XP_017209219.1	Gene:	adcy6a / 570652	ZFINID:	ZDB-GENE-060221-1	Length:	1203	Species:	Danio rerio

Alignment Length:	299	Identity:	83/299 - (27%)
Similarity:	139/299 - (46%)	Gaps:	59/299 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1051 FQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEF--------- 1106
            ||....|......|.||..:|        |:||..:||..||.::|..:....|:.
Zfish   345 FQETRGYIQARLHLQRENQQQ--------ERLLLSVLPRHVAMEMKADINAKKEDMMFHKIYIQK 401

  Fly  1107 -SDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVK 1170
             .:|:|.|:||.|||::|:.|:..::|..||:|:..||...:..:..:::.:||.|..|||||..
Zfish   402 HDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLASENHCLRIKILGDCYYCVSGLPEP 466

  Fly  1171 IPDHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTA 1235
            ..|||.....|.:|::.....  |:.:.||.:.:|:|:|:|....||:||...::.::.:.|..|
Zfish   467 RADHAHCCVEMGVDMIEAISL--VREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLA 529

  Fly  1236 SRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKGKG----------MMNTFWLLGKKGF 1290
            :.||:.|.:.|||:::.|...|:  |.|.:||       |.|          .:.||.:||....
Zfish   530 NHMEAGGKAGRIHITKATLQYLN--GDYEVEP-------GFGGERNAYLKENSIETFLVLGCSQK 585

  Fly  1291 DKPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTN 1329
            .|              ||.      .:.|:..::||::|
Zfish   586 RK--------------DEK------AMMAKMQRTRTNSN 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	61/201 (30%)
adcy6a	XP_017209219.1	AC_N	<97..395	CDD:318454	16/57 (28%)
		Guanylate_cyc	397..570	CDD:306677	56/183 (31%)
		DUF1053	609..696	CDD:310728
		Guanylate_cyc	1004..1197	CDD:306677
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900