DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34357 and adcy6b

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	XP_002666536.2	Gene:	adcy6b / 560807	ZFINID:	ZDB-GENE-090127-2	Length:	1174	Species:	Danio rerio

Alignment Length:	310	Identity:	85/310 - (27%)
Similarity:	149/310 - (48%)	Gaps:	47/310 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1072 LDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEF----------SDVTIYFSDIVGFTTIAAHC 1126
            |..|.::.|:||..:||..||.::|..:....|:.          .:|:|.|:||.|||::|:.|
Zfish   339 LQRENQQQERLLLSVLPRHVAMEMKADINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQC 403

  Fly  1127 SPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIPDHAEQIATMALDLLHQSGR 1191
            :..::|..||:|:..||......:..:::.:||.|..|||||....|||.....|.:|::.....
Zfish   404 TAQELVMTLNELFARFDKLAWENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISL 468

  Fly  1192 FNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDR 1256
              |:.:.||.:.:|:|:|:|....||:||...::.::.:.|..|::||:.|.:.|||:::.|...
Zfish   469 --VREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAGRIHITKATLQY 531

  Fly  1257 LDARGGYAIEPRGLIDIKGKG----------MMNTFWLLG---KKGFDKPLPAP---PPIGESHG 1305
            |:  |.|.:|       .|.|          .:.||::||   |:..:|.:.|.   .....|.|
Zfish   532 LN--GDYEVE-------AGFGGDRNAYLNNNNIETFFVLGCSQKRKEEKAMMAKMQRARANSSEG 587

  Fly  1306 L------DESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEI 1349
            |      |.|..|.    |......:...:.:||:.:..|.|::..:.|:
Zfish   588 LMPRWVPDRSFSRT----KDSKVFRQMGIDEASSKDNRCAQEALNPEDEV 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	62/201 (31%)
adcy6b	XP_002666536.2	AC_N	15..376	CDD:318454	11/36 (31%)
		Guanylate_cyc	378..562	CDD:306677	57/194 (29%)
		DUF1053	590..677	CDD:310728	9/48 (19%)
		Guanylate_cyc	975..1169	CDD:306677
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810