Protein Alignment CG34357 and CG43373

DIOPT Version :9

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Alignment Length: 1848
• Identity: 370/1848 - (20%)
• Similarity: 609/1848 - (32%)
• Gaps: 598/1848 - (32%)

  Fly    58 SEKPLHSDVLV--LRAAKPSRAIATSADAATR--SVPASAAETTLGSKSIW----PTAIQTKSPR 114
            ||..|.::..|  |..|........|:|..||  |:|..|    |.|...|    ....:.||..
  Fly   307 SEIGLDANATVGNLTTATMKPPTLASSDQMTRGSSIPLLA----LASNGSWAGNGAVGGELKSAH 367

  Fly   115 NAREA---GRHKRQMQKPAIQQQPLQQQQQRINPPQQKRQQQQQQQQQVQHQAQRVGVLIPPSLH 176
            |...|   ..|..|:    :.::..::..:|::..:.|.:..||.:.:.:.:.:|       ||.
  Fly   368 NHNIADFEADHNGQL----VWRRQKRKHYRRLHKHRYKHKSHQQHRTRYRMREKR-------SLQ 421

  Fly   177 VDLTHVQ-QGFQNFLDFFQLHLFNVTVDFLRDVDLSGFIKLLELPKYTSVIKTLNAGIMVASHVD 240
             |...|: .|.|.     ||.:...|.|   |.|:           ||           |||..|
  Fly   422 -DAGLVKGGGIQT-----QLIVDTATDD---DADV-----------YT-----------VASDDD 455

  Fly   241 VDQNSTIYIGTPSQPRQQHRLHSKQEQEPHRHHHEDSKAKQFPAGEEE----SHSSGETEENHWN 301
            .|.:.....|:      :|..::.:.::.::..|         |..:|    |.::|...:|  :
  Fly   456 DDVDGGRSAGS------KHITYTPRVRDYNQISH---------AERDEVLNTSSNAGVATDN--S 503

  Fly   302 DARIFSGHCHQLAEQLALDFNKTVVLWPCPRM--KISSNFL------PSFEAISLAVQSISTKLN 358
            |..:..|   ||...:.:..:::|:::....:  .|...||      |:...|.|.:.|
  Fly   504 DPPLGYG---QLIPLILMQVDESVLVFLIVMLICGIVYAFLLCILSKPAMNEIFLVLVS------ 559

  Fly   359 WSQVDIYIGDDNWGLGLAIAANLHVPYRIEIGRTIRDLHSQDKPGKAIIIT--------APLNDA 415
                  |:     .||..:|..:.|.|.::..::..        |.|..|.        .||...
  Fly   560 ------YV-----ILGTFLAIEVAVSYAMQPSKSFN--------GSACCIVLIYMTYTMLPLRLR 605

  Fly   416 STI---LLLSTIELDWTEQARKDGQGSRPGRQHTKILLIDMAASSLDTQHGFYKYLSRMGGSQSD 477
            ..:   :|||.:.| :|.......|.......|.:.||..:.|..|....|.|.:..: ..:|..
  Fly   606 EALIGGILLSVVHL-YTCLRLNAMQDEAVEMIHWEELLCTLVALLLANLTGVYTHWPK-EKAQRK 668

  Fly   478 AFARNTGSPAEVVSSNLLVLTLLNDRHRLFLNAAGLMATMQNFRAPLNGNYKDPPPSGHRNASLH 542
            ||...    .:.:.:.|........:.||.|:.......|:         .||......|:...|
  Fly   669 AFIET----RQCIEARLRTQRENQQQERLLLSVLPRHVAME---------MKDDIAGQPRDTQFH 720

  Fly   543 KLYPYR--NLLPLYDTIVTTTTQSD--TSETSPQFDFVVLDIVR---------DAPVATYKWRPL 594
            |:|..|  |:..|:..|...|:.||  |:|          ::||         |...|.:....:
  Fly   721 KIYIQRHENVSILFADICGFTSLSDQCTAE----------ELVRLLNELFARFDRLAAEHHCLRI 775

  Fly   595 LILESDPGSRGGGSVVEGGGSY--ISHSIHPGYDEWLLVSSVLLWQCGAICWTIAAICVCLLVIM 657
            .:|               |..|  :|....|..|.             |.|.....:.:...:.:
  Fly   776 KLL---------------GDCYYCVSGLPEPRPDH-------------AHCAVEMGLDMIDAIAL 812

  Fly   658 IAGIVAGGIAMRNYFLRKRLSKGPNKIVLSASDFVFPVDSRRV-------DEGIEAMLCCWLQQL 715
            :..::|..:.||......|:..|    ||....:.|.|.|..|       ..||...:....:.|
  Fly   813 VREVMAVNVNMRVGIHTGRVHCG----VLGLVKWQFDVWSNDVTLANHMESGGIPGRVHITKETL 873

  Fly   716 QEFGGP---EVDKPDLLKGSIGSLKN---------LGFVIPG-AAAPGSAGAITTTANGKSGSS- 766
            :...|.   ||.|        |:.:|         ...::|| ...|..........||.....
  Fly   874 KCLDGDYEVEVGK--------GNERNSYLKDHQIETYLIVPGDIYRPHKKSRNRLQVNGNISKEL 930

  Fly   767 ---ATGSLARHNPAHLDMRARYN-GDLVQL-----KEVNINGSAELRTKAMDLLVMAHGLRHENI 822
               ..|:..:|.       :::. ||..:.     .|||     |...:|:|...:.| ||.|:.
  Fly   931 RMMGHGTAQKHT-------SKFGFGDSSESAKDPEDEVN-----EYLMRAIDARSIDH-LRAEHC 982

  Fly   823 NPLI----------GWLSDPNRTAMVFDYCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVRGMRYL 877
            ..|:          .:.|:|:|...|:.|||...|....||..:    .|:.||||      ..|
  Fly   983 QSLLLCFKDNVLERKYASEPDRMLCVYFYCSLLVLLGTSIMRLV----VFQSSLLT------LAL 1037

  Fly   878 HTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLRNMKLHQ 942
            .|..|.:.|.|           |..:..:.:|                   :..|..::...|
  Fly  1038 STGALLLLGFL-----------VFLVACHKIN-------------------FQLPSDIKRFSL-- 1070

  Fly   943 HHHQHGRIQLGTQLGDVYSFGIIMQEVV-------------------------VRGEPYCMLSLS 982
                  ||....::..:::|..:...|:                         |.|.    :||:
  Fly  1071 ------RIHSNRRISQLFAFASVALIVLTTLLAMFQESGRQMELLQRRRFWLDVNGS----ISLN 1125

  Fly   983 PEEIIVKIKKPPPLIRPSVSKGAAPPEAINIMRQCWAEQPDMRPDFNSVYERFKMLN-------- 1039
            ..|:..|:..                          ||:||.  ||...|..|.:|.
  Fly  1126 DTELNTKMYD--------------------------AEEPDC--DFYLAYNTFLLLTLLSMMSCA 1162

  Fly  1040 -----------------HGRKVNFVDTMFQMLEKYSNNL---EELIR------------------ 1066
                             .|..:.....::....:.|..|   |.|:|
  Fly  1163 TYQVLRILLKLLLLLLASGSYMACSSNLYSRSREMSQELANEEALLRYIIDSIFLFAFMLALIFH 1227

  Fly  1067 ----ERTEQLDI-------ERKK--------TEQLLNRMLPSSVAEK-LKMGLAVDP---EEFSD 1108
                |.|.:||.       |.|:        ..:||..:||..|||. |.....:|.   |:...
  Fly  1228 SHQTEATYRLDFIWKLQATEEKEDMEHLQAYNRKLLENILPVHVAEHFLSREKHLDDLYHEQCDS 1292

  Fly  1109 VTIYFSDIVGFT----TIAAHCSPVQVVDLLNDLYTIFDATINAYN---VYKVETIGDAYMVVSG 1166
            |.|.|:.|..|:    .:..:...|:.:.|||::...||..::...   :.|:::.|..||..||
  Fly  1293 VCILFASIPNFSEFYVELEGNNEGVECLRLLNEIIADFDELLSEERFRCIEKIKSTGATYMAASG 1357

  Fly  1167 LPVKIPD-----HAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYC 1226
            |.....|     |...:|..||.|..:....|:.....  .::|||::.||..|||:|...|:|.
  Fly  1358 LTANTCDRVNFSHVTAMADYALQLFDKIEEVNMHSFNN--FRMRIGINIGPVVAGVIGACKPQYD 1420

  Fly  1227 LFGDTVNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKGKGMMNTFWLLGKKGFD 1291
            ::|:.||.||||:|||....|.::||.:..|:.| |:.:..||.:|:||||.|.|::|.|::..|
  Fly  1421 IWGNAVNVASRMDSTGLVDHIQVTQEMQQILEGR-GFELTCRGSVDVKGKGSMITYFLKGRRPID 1484

  Fly  1292 -------KPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEI 1349
                   |....||              .::||..:..|..:.|.....:.......|.|.:.::
  Fly  1485 AKELELAKTEVEPP--------------KTLTLAKEPEKLDSGTATEKQREQVKEQGSTEQEDDL 1535

  Fly  1350 TPPTNADLASGTNLPNSYSLDSNSTNTISPNATLCPEFPGKTTPSSTSPQSRKLSELTPENLLNP 1414
            .|..:.|:.|     |..:|.:....::.....:...| |.|..|||.        :||.
  Fly  1536 LPSPDIDMNS-----NMQNLTAQRRKSLCRQHNISSSF-GTTVSSSTG--------ITPS----- 1581

  Fly  1415 NSFNRLPSSTGGSSSRLYKKIEEMMDLSSPYNHYKCLSPSESNLTQFYDGKYLYGSVAGGAGGGQ 1479
                                                :|.|.|.:|        .|::.....||.
  Fly  1582 ------------------------------------ISNSSSVVT--------IGALPAILRGGN 1602

  Fly  1480 AGGGACASIALSGSGCGGGASRFDSKPGSSRLLRRQFSLDRDDQQAKGEQQHHQHSLQANTYSGL 1544
            ....|..:...|.|.|||.:....:.....|.|    ..|..|:.|:.|:.
  Fly  1603 PLSNANPNATDSCSECGGASKSLATPTAPPRTL----VADLKDEIARDEKI-------------- 1649

  Fly  1545 VGGCGGGVKSSM--LDIPLLHDTTRSPKGTLTRSHKQN-----SASITQDLEKIEEI-------- 1594
                  |:|.|:  |:|.|.::.:.|   .|:...:||     |:|.|..|.|.:.|
  Fly  1650 ------GLKDSIENLEILLKNNISLS---DLSNKQQQNLRGETSSSTTTTLRKRDTIVSFNVTET 1705

  Fly  1595 ------PLSPASSQHHSSLDSNLNRSPPSTLEAQSPPLPPMSPPQLSAPTSPAPSRTLNGIYAHN 1653
                  |.:.:|...:||......|| .:|:.|..              |:...:|.|:.   .:
  Fly  1706 VTTTAAPFTSSSGSSNSSSQQKKRRS-VTTIAASF--------------TTSTTTRLLSN---ES 1752

  Fly  1654 SNSTSSHGAANNNNGTHPGPELTLNAEQ 1681
            .:||.:......:.|:.||...|.|:.|
  Fly  1753 QSSTQTAPGTLESGGSVPGQSSTENSSQ 1780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	58/347 (17%)
		CYCc	1074..1266	CDD:214485	64/222 (29%)
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	43/236 (18%)
		CYCc	686..881	CDD:214485	46/245 (19%)
		Guanylate_cyc	722..895	CDD:278633	42/222 (19%)
		DUF1053	<949..1005	CDD:283888	14/61 (23%)
		CYCc	1259..1455	CDD:214485	61/198 (31%)
		Guanylate_cyc	1285..1479	CDD:278633	63/196 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810