DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34357 and Ac3

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	NP_610116.2	Gene:	Ac3 / 35419	FlyBaseID:	FBgn0023416	Length:	1167	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	86/315 - (27%)
Similarity:	146/315 - (46%)	Gaps:	50/315 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1065 IRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLA-----VDPEEFSDVTIYFSDIVGFTTI-- 1122
            :.|:.|..:..|::.|.|:..:||..|||.......     :..:.:::|.:.|:.:..|:..
  Fly   851 VAEQKETANDMRQRNEALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFYS 915

  Fly  1123 --AAHCSPVQVVDLLNDLYTIFDATINA---YNVYKVETIGDAYMVVSGLPVK------IP---- 1172
              ..:...::.:..||::.:.|||.:..   .::.|::|||..||..||:.|:      .|
  Fly   916 EETVNNQGLECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQRTVRNDAPITER 980

  Fly  1173 -DHAEQIATMALDLLHQSGRFN---VKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1233
             .|...:...||:|.|.....|   ..|     ..|::|::.||..|||:|...|.|.::|:|||
  Fly   981 WSHLAILVEFALELKHALQSINEQSFNH-----FVLKMGINHGPITAGVIGARKPHYDIWGNTVN 1040

  Fly  1234 TASRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKGKGMMNTFWLLGKKGFDKPLPAPP 1298
            .||||||||.:..|.:::||.:.| ...||....|||:.:||||.:.||:|.||.. ....|...
  Fly  1041 VASRMESTGKAGAIQVTEETCNIL-RLFGYTFLQRGLVAVKGKGQLMTFYLQGKSQ-SSAEPVAS 1103

  Fly  1299 PIGESHGLDESLIRNSITLKA-----------------QANKSRTSTNPSSSQSS 1336
            .:...:|.|.|.:.::..|:|                 :.::.|:..|.|:.|.|
  Fly  1104 GVVVLNGQDSSAVESTSELEASDIKMPLLKMNGPEQSLEIDQDRSLRNDSAGQES 1158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	61/217 (28%)
Ac3	NP_610116.2	AC_N	<127..285	CDD:292831
		CYCc	256..453	CDD:214485
		Guanylate_cyc	294..476	CDD:278633
		CYCc	860..1071	CDD:214485	61/216 (28%)
		Guanylate_cyc	892..1092	CDD:278633	63/205 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810