DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG34357 and rut

DIOPT Version :9

Sequence 1:NP_001356914.1 Gene:CG34357 / 5740349 FlyBaseID:FBgn0085386 Length:1689 Species:Drosophila melanogaster
Sequence 2:NP_511156.2 Gene:rut / 32406 FlyBaseID:FBgn0003301 Length:2248 Species:Drosophila melanogaster


Alignment Length:626 Identity:146/626 - (23%)
Similarity:229/626 - (36%) Gaps:199/626 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1037 MLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAV 1101
            |:...::..|:||            ...|..|.|..| |.:|.|:||..:||..||.::|..: :
  Fly   206 MMERAQRRTFLDT------------RNCIASRLEIQD-ENEKLERLLLSVLPQHVAMQMKNDI-L 256

  Fly  1102 DP----------EEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVET 1156
            .|          ::..:|:|.|:||||||.:::.||..::|.|||:|:..||...:..:..:::.
  Fly   257 SPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKI 321

  Fly  1157 IGDAYMVVSGLPVKIPDHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLT 1221
            :||.|..|||||....|||:....|.||::....  .|.....|.|.:|:|:|||....||:||.
  Fly   322 LGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIA--TVVEATDVILNMRVGIHTGRVLCGVLGLR 384

  Fly  1222 MPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKGKGMMNTFWLLG 1286
            ..::.::.:.|..|:.|||.|...|:|:::.|.|.|.  |.|.:|       .|.|...:.: |.
  Fly   385 KWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLS--GEYEVE-------AGHGDERSSY-LR 439

  Fly  1287 KKGFDKPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEITP 1351
            ..|.|.....|||...     :.|:.|::.:::                                
  Fly   440 DHGVDTFFIVPPPHRR-----KPLMLNTLGVRS-------------------------------- 467

  Fly  1352 PTNADLASGTNLPNSYSLDSNST----NTISPNATLCPEFPGKTTPSSTSPQSRKLSELTPENLL 1412
                  |.|:....|:...||..    :||                        |.||..|.:.:
  Fly   468 ------AIGSRRKLSFRNVSNVVMQLLHTI------------------------KFSEPVPFSNI 502

  Fly  1413 NPNSFNRLPSSTGGSSSRLYKKIEEMMDLSSPYNHYKCLSPSESNLTQFYDGKYLYGSVAGGAGG 1477
            ...||....|:.||..                                         ||.||.||
  Fly   503 ATGSFPSAASALGGGV-----------------------------------------SVGGGGGG 526

  Fly  1478 GQAGGGACASIALSGSGCGGGASRFD-SKPGSSRLLRRQFSLDRDDQQAKGEQQHHQHSLQANTY 1541
            |  |||..     .||.|...:.... |:.||.:::|.|..|            |.........|
  Fly   527 G--GGGVA-----RGSTCEANSGNVQVSEKGSRKVIRLQKIL------------HATPPPHGMGY 572

  Fly  1542 SGLV-------------GGC-------GGGVKSSMLDIPLLHDTTRSPKGTLTRSHKQNSASITQ 1586
            ..:|             |||       ||||:.::...|      .|...|::|.|:.|..: .:
  Fly   573 GSVVGSGGGVDSGISGGGGCVSGGIAGGGGVQVTVGTNP------NSTASTISRIHRHNHKN-NK 630

  Fly  1587 DLEKIEEIPLSPASSQH----HSSLDSNLNRSPPSTLEAQS 1623
            ...|:.:....|...:|    |....:.:||.....:.|:|
  Fly   631 SQSKVADKFKRPFRKRHSVAAHHQPTNRVNRFLSQAINARS 671

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34357NP_001356914.1 PKc_like 763..1041 CDD:354810 1/3 (33%)
CYCc 1074..1266 CDD:214485 68/201 (34%)
rutNP_511156.2 AC_N <17..255 CDD:292831 18/61 (30%)
CYCc 230..425 CDD:214485 68/200 (34%)
Guanylate_cyc 266..438 CDD:278633 60/183 (33%)
DUF1053 624..696 CDD:283888 9/49 (18%)
SLC5-6-like_sbd <742..>893 CDD:294310
CYCc 924..1134 CDD:214485
Guanylate_cyc 954..1151 CDD:278633
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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