Protein Alignment CG34357 and GUCY1A2

DIOPT Version :9

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: NP_001243353.1
• Gene: GUCY1A2 / 2977
• HGNCID: 4684
• Length: 763
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 102/260 - (39%)
• Similarity: 135/260 - (51%)
• Gaps: 39/260 - (15%)

  Fly  1041 GRKVNFVDTMFQMLEKYSNNLEELIRERTEQ-LDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPE 1104
            |.:....|.:.:.::|....|     |||.| |:.|:|||..||..:.|..||::|..|..|...
Human   456 GEQAKAQDGLKKRMDKLKATL-----ERTHQALEEEKKKTVDLLYSIFPGDVAQQLWQGQQVQAR 515

  Fly  1105 EFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPV 1169
            :|.|||:.||||||||.|.|.|:|:||:.:||:|||.||......::||||||||||.|.:||..
Human   516 KFDDVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGFLDIYKVETIGDAYCVAAGLHR 580

  Fly  1170 KIPDHAEQIATMALDLLHQSGRFNVKHLPGVPLQ------------------------------- 1203
            |...||:.||.|||.::..|.  .|....|.|:|
Human   581 KSLCHAKPIALMALKMMELSE--EVLTPDGRPIQPQRSELLFSFPVSIQLVPDQHQSETDLGTEK 643

  Fly  1204 LRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPR 1268
            :|||:|:|...|||||:.||||||||:.|..||:.||.....||::|..|...|.....:...||
Human   644 MRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRRINVSPTTYQLLKREESFTFIPR 708

  Fly  1269  1268
            Human   709  708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	102/260 (39%)
		CYCc	1074..1266	CDD:214485	91/222 (41%)
GUCY1A2	NP_001243353.1	HNOB	<159..270	CDD:285002
		HNOBA	316..503	CDD:285003	16/51 (31%)
		CYCc	485..705	CDD:214485	91/221 (41%)
		Guanylate_cyc	514..729	CDD:278633	81/197 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810