DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34357 and Adcy10

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	NP_766617.2	Gene:	Adcy10 / 271639	MGIID:	2660854	Length:	1614	Species:	Mus musculus

Alignment Length:	308	Identity:	68/308 - (22%)
Similarity:	110/308 - (35%)	Gaps:	109/308 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   966 MQEVVVRGEPYC-------MLSLS--PEEIIVKIK--KPPPLIRPSVSKGAAPPEAINIMRQCWA 1019
            |.:|::  .|.|       |:.:.  |::..||:.  ||||.....           ....:|..
Mouse   184 MNDVIL--SPNCWQLCDRSMIEIERIPDQRAVKVSFLKPPPTFNFD-----------EFFTKCMG 235

  Fly  1020 EQPDMRPDFNSVYERFKMLNHGRKVNFV--------DTMFQM-LEKYSNNLEELIRERTEQLDIE 1075
                    |...|.      .|...||:        |...:: |:||   :.|:|.::     |:
Mouse   236 --------FMDYYP------SGDHKNFLRLACMLESDPELELSLQKY---VMEIILKQ-----ID 278

  Fly  1076 RKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYF----------SDIVGFTTIAAHCSPVQ 1130
            .|:....|:.:.|                    |||.|          .:::| :.|.|.|  |.
Mouse   279 DKQLRGYLSELRP--------------------VTIVFVNLMFKEQDKVEVIG-SAIQAAC--VH 320

  Fly  1131 VVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLP-VKIPD---HAEQIATMALDLLHQSGR 1191
            :..:|.    :|...||  .|:..:. |.:::.|.|.| .|.||   ||.:.|....|...|..:
Mouse   321 ITSVLK----VFRGQIN--KVFMFDK-GCSFLCVFGFPGEKAPDEITHALESAVDIFDFCSQVHK 378

  Fly  1192 FNVKHLPGVPLQLRIGLHTGPCCAGVVGLTM-PRYCLFGDTVNTASRM 1238
            ...         :.||:.:|....|:||.|: ..|.:.|..||.|:||
Mouse   379 IRT---------VSIGVASGIVFCGIVGHTVRHEYTVIGQKVNIAARM 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	15/85 (18%)
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	44/180 (24%)
Adcy10	NP_766617.2	CHD	40..214	CDD:143636	6/31 (19%)
		CHD	292..461	CDD:143636	40/145 (28%)
		COG3899	485..>959	CDD:226415
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900