DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34357 and gcy-36

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	NP_510557.3	Gene:	gcy-36 / 191657	WormBaseID:	WBGene00001556	Length:	675	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	110/249 - (44%)
Similarity:	159/249 - (63%)	Gaps:	7/249 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly  1037 MLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAV 1101
            :||. ::::.|:...| ||..:..||.:.::    |::|:.||:.||..|||.|||::||.||:|
Worm   383 LLNQ-QRLSDVEMNLQ-LEANNEQLENMAKD----LEVEKGKTDALLREMLPPSVAQQLKQGLSV 441

  Fly  1102 DPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSG 1166
            :..|:.:.|:.|:|:..|..|...|:|..:|.|||:|:|.||..|.....|||||:||:||.|.|
Worm   442 EAREYEEATVMFTDVPTFQQIVPLCTPKDIVHLLNELFTKFDRLIGIQKAYKVETVGDSYMSVGG 506

  Fly  1167 LPVKIPDHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDT 1231
            :|..:.||.|.|..:||.::.:: |.....:...||.:|.|:|:||..|||||..||||||||||
Worm   507 IPDLVDDHCEVICHLALGMVMEA-RTVCDPITNTPLHIRAGIHSGPVVAGVVGAKMPRYCLFGDT 570

  Fly  1232 VNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKGKGMMNTFWLL 1285
            |||:|||||.....|||.|:..:...::.|.:..||||.:.|||||.|||::||
Worm   571 VNTSSRMESHSPIGRIHCSENAKKCAESTGRFEFEPRGRVQIKGKGEMNTYFLL 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	2/3 (67%)
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	87/191 (46%)
gcy-36	NP_510557.3	HNOB	3..167	CDD:285002
		HNOBA	217..435	CDD:285003	20/57 (35%)
		CYCc	415..604	CDD:214485	87/189 (46%)
		Guanylate_cyc	441..624	CDD:278633	84/183 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810