Protein Alignment CG34357 and gcy-27

DIOPT Version :10

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: NP_001255957.2
• Gene: gcy-27 / 191654
• WormBaseID: WBGene00001550
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 163/520 - (31%)
• Similarity: 271/520 - (52%)
• Gaps: 46/520 - (8%)

  Fly   791 QLKEVNINGSAELRTKAMDLLVMAHGLRHENINPLIG-WLSDP-NRTAMVFDYCSRGSLQDVLIM 853
            |:|.::|..:      ::|.|.....|:|:|:....| .|:|. |...::.....||:|::..:.
 Worm    95 QIKHIDITNA------SLDFLYNLKQLKHDNLANFYGIQLNDDLNTMTILHALVERGTLEEFCLD 153

  Fly   854 DEIKLDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFY------ 912
            .:..:|.:|:.:.:.|:::|::|||.||:..||.|.:..|::|..|||||..||:.:|.
 Worm   154 RDFGMDETFKSAFMRDILKGLQYLHLSPVAYHGHLHAATCLIDINWVLKIALYGVTNFVCDNFDA 218

  Fly   913 ESQGLPPR---TRSAKELLWTAPELLRNM----KLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVV 970
            |:..:|.|   |.|..:.:...||.:|..    ||..      |...|::.||:|..|:|...::
 Worm   219 ENITMPDRSDYTISYAQYVCFPPEHIREYDATGKLPT------RFVRGSKQGDIYCVGMIFYMMI 277

  Fly   971 VRGEPYCMLSLSPEEIIVKIKKP---------PPLIRPSVSKGAAPPEA-INIMRQCWAEQPDMR 1025
            .|.:||        .:|..:::|         ...:.|.:|......:. ::..::||...|:.|
 Worm   278 EREDPY--------RLIHSVERPGSGLMMEILDHNLMPFISNNETQEDTLLDKCKECWNRDPEKR 334

  Fly  1026 PDFNSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSS 1090
            |...::.....:.....|.|.:|.|.:|.|||::.||.|:..|:..|.:.:.:|.:|||.|||:|
 Worm   335 PTIENLRNAIAICYADSKGNLIDQMIRMNEKYADELETLVAARSADLALAQMQTMRLLNEMLPAS 399

  Fly  1091 VAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVE 1155
            :|:.||.|:......::..|:.|..|..|..|.....|.:|:..|||::..||..|..::.||||
 Worm   400 IAKDLKNGVIAPARSYASATVMFVQICDFIVILKRRPPKEVIGFLNDIFDQFDTVIKRHDAYKVE 464

  Fly  1156 TIGDAYMVVSGLPVKIPD-HAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVG 1219
            |.|:.|||.||:|.:... |..::|.|:|::...|..:.:::.....|::|||.|.||..|||:|
 Worm   465 TTGETYMVASGVPNENEGRHVFEVAEMSLEIRAISLSYTLENDKNYKLRVRIGFHAGPIAAGVIG 529

  Fly  1220 LTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKGKGMMNTFWL 1284
            :..|||||||||||.||||:|.....:|..|:.|...|.|...|.:..||::.:||||.:|.:||
 Worm   530 IKNPRYCLFGDTVNFASRMQSNCPPLQIQTSEITARMLLATHEYKLVKRGIVHVKGKGEVNCYWL 594

  Fly  1285  1284
             Worm   595  594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	Protein Kinases, catalytic domain	763..1041	CDD:473864	66/274 (24%)
		HNOBA	<1047..1095	CDD:462234	20/47 (43%)
		CYCc	1074..1266	CDD:214485	75/192 (39%)
gcy-27	NP_001255957.2	Protein Kinases, catalytic domain	75..338	CDD:473864	66/262 (25%)
		CYCc	383..573	CDD:214485	74/189 (39%)