Protein Alignment CG34357 and gcy-11

DIOPT Version :9

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: NP_001359843.1
• Gene: gcy-11 / 181745
• WormBaseID: WBGene00001537
• Length: 1168
• Species: Caenorhabditis elegans
• Alignment Length: 1199
• Identity: 329/1199 - (27%)
• Similarity: 508/1199 - (42%)
• Gaps: 312/1199 - (26%)

  Fly   326 VLWPCPRMKISSNFLPSFEAISLAVQSISTKLNWSQVDIYIG-------DDNWGL---GLAIAAN 380
            :||....:..||:.:..|...:.   ::..|.::...|.|:|       :|..|:   |..:.::
 Worm     8 LLWILVPIASSSDHITFFGRYAC---NVDFKTDYCTPDTYVGRAFYYGLEDGGGITTNGTFVNSD 69

  Fly   381 LHVPY-------RIEIGR------------TIRDLHSQD---------KPGKAIIITAPLNDAST 417
            :.|.:       ...|||            .:.|....|         ...|.|...|...|||:
 Worm    70 ITVEFFDPTVQGNFSIGRQDGNYMSSMLDIMLADTKKNDGLLGVVGVENDCKEIAALAQAYDASS 134

  Fly   418 ILLLSTIELDWTEQARKDGQGSRPGRQHTKILLIDMAASSLDTQHGFYKYLSRMGGSQSDAFARN 482
            :|      ::..:|.   |:...|.         ..|.....||.|.|:..:::        |::
 Worm   135 LL------VNCEDQV---GESQMPS---------STALQMSSTQGGKYRAFAKL--------AKS 173

  Fly   483 TG------------SPAEVVSSNLLVLTLLNDRHRL-FLNAAGLMATMQNFRAPLNG-------- 526
            .|            .||::...:.|:..|..:...| |:...|..:|:.:  |...|
 Worm   174 VGWNNLAVINFVEDGPADISYHDQLLDALSAESISLDFVKKGGFSSTITS--AMFTGLESVIDVI 236

  Fly   527 --NYK---------DPPPSG--HRNASLHKLYPYRNLLPLYDT-----IVTTTTQSDTSETSPQF 573
              .|.         |.|.||  ..||        .:.:.|.:|     ::.::.:||.:.   .|
 Worm   237 LETYMKTRIYVIVLDLPVSGTFFMNA--------MSTMGLLETGKYFVVMMSSIESDAAN---YF 290

  Fly   574 DFVV---------LDI-VRDAPVATY-------------------KWR----------------P 593
            .|.|         :|. :.||.:..|                   :|.                |
 Worm   291 GFNVNRGNMIFKTIDYGISDADIRQYYRSFMYFTDVPHYTKDFSDEWTSFQKRVDGDASKTFCPP 355

  Fly   594 LL------ILESDPGSRGGGSVVEGGGSYISHSIHPGYDEWLLVSSV-------LLWQCGAICWT 645
            :.      |..:||.|.......|      |.||...||...|:|..       ||....::..|
 Worm   356 MCNTKAKGIANNDPWSDDAYWYSE------SPSIVDAYDLGRLLSETVKVHGASLLRDPESLVQT 414

  Fly   646 IAAICVCLLVIMIAGIVAGGIAMRNYFL----RKRLSKGPNKIVLSASDFVFPVDSRRVDEGIEA 706
            ::...|..|:..:......|::.|.|.|    :...|.||..:...|:     :.:|.:.:|...
 Worm   415 MSGRGVTSLLGYVTKFNTNGVSQREYILWAPQQASSSNGPIPLPEWAT-----LAARMLPDGKGN 474

  Fly   707 MLCCW--LQQLQEFGG--PEVDKP------DLLKGSIGSLKNLGFVIPGAAAPG---SAGAITTT 758
            ....|  |.||..|.|  |: .||      :|....|.:|..|..::.......   ..|.|...
 Worm   475 YSIIWKNLTQLGIFNGELPQ-SKPECGFNNELCPAGIRNLSELEIIVIAVCVVAILILVGVIAYI 538

  Fly   759 AN-------------------------GKSGSSATGSL--------------------------- 771
            |.                         .|.|||..||:
 Worm   539 ARWIAYERRLESSYFLVHRKHVQLVDMTKFGSSRGGSMIQSAMSMRSQYEDSGPVGGATMNFYTN 603

  Fly   772 ------ARHN--------PA------------HLDMRARYNGDLVQLKEVN---INGSAELRTKA 807
                  .|.|        ||            ||   |:|...||.::::|   :..:.|:: :.
 Worm   604 GIRKAAIRRNQMQRSDKGPAANRDEWLEIVDWHL---AKYENTLVTVRKINKTQLKLTREMK-QE 664

  Fly   808 MDLLVMAHGLRHENINPLIGWLSDPNRTAMVFDYCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVR 872
            :|||:   ...|||:|...|.:::.:....:..|..|.||.|:|..|:::||..|::|.:.|:|:
 Worm   665 IDLLM---NETHENLNRFFGLINESDLIFTIHSYGPRKSLMDLLRNDDLRLDRMFKVSFVEDVVK 726

  Fly   873 GMRYLHT-SPLRVHGALTSRNCVVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLR 936
            |:::||. |.:..||.|.|.||:|||.|.:|:::||:......:   |.:: ..:|||.|||::|
 Worm   727 GLQFLHEGSKIGYHGNLKSSNCIVDAYWRIKLSNYGMEQIRVEE---PESK-PDDLLWFAPEIIR 787

  Fly   937 NMKLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVVVRGEPYCMLSLSPEEIIVKIKKPP--PLIRP 999
            ...:   .|...:::|..  .|:||..|::.|:..|..|:....|..:|||.::|.|.  .|.||
 Worm   788 RYAV---KHDLSKLELAK--ADIYSLAIVLYEIYGRQGPFGDDLLDSDEIIEQLKFPDGGALTRP 847

  Fly  1000 S---VSKGAAPPEAINIMRQCWAEQPDMRPDFNSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNL 1061
            .   ::|  ||....:::.:||.|.|..||....|.|..|.|:.|.|.|..|.:..:|::|.|||
 Worm   848 DIHLITK--APYPLASVVEKCWVEDPASRPSIKKVRELLKPLSKGLKGNIADNIMNLLDRYRNNL 910

  Fly  1062 EELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHC 1126
            |::|:||||||:.|||:.|.||.::||.|||..||.|..||.|.:..|:||||||||||.:::..
 Worm   911 EDVIKERTEQLEDERKRNESLLLQLLPKSVANSLKNGQPVDAEFYDSVSIYFSDIVGFTALSSKS 975

  Fly  1127 SPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLP-VKIPDHAEQIATMALDLLHQSG 1190
            :|:|||::||:|||.||..|:.::.|||||||||||.||||| |....||.::|:.:|:||....
 Worm   976 TPLQVVNMLNNLYTNFDTIIDKFDCYKVETIGDAYMFVSGLPEVNSYLHAGEVASASLELLDSIK 1040

  Fly  1191 RFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRD 1255
            .|.|.|.|...|:||||.||||...||||:.|||||||||||..|:.|||:|...||.:|.:..:
 Worm  1041 TFTVSHCPDEKLRLRIGNHTGPVVTGVVGIRMPRYCLFGDTVIIANMMESSGEPMRIQISSDAYE 1105

  Fly  1256 RLDARGGYAIEPRGLIDIKGKGMMNTFWL 1284
            .:...|||..|.|..|.:|.|..:.|:|:
 Worm  1106 LILKCGGYVTEQREKIVLKNKLEVMTYWM 1134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	94/339 (28%)
		CYCc	1074..1266	CDD:214485	102/192 (53%)
gcy-11	NP_001359843.1	Periplasmic_Binding_Protein_type1	<234..452	CDD:385651	41/234 (18%)
		PKc_like	640..890	CDD:389743	82/264 (31%)
		CYCc	923..1116	CDD:214485	102/192 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I6309
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820