Protein Alignment CG34357 and Adcy3

DIOPT Version :9

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: NP_612178.2
• Gene: Adcy3 / 104111
• MGIID: 99675
• Length: 1145
• Species: Mus musculus
• Alignment Length: 554
• Identity: 135/554 - (24%)
• Similarity: 225/554 - (40%)
• Gaps: 134/554 - (24%)

  Fly   915 QGLPPRTRSAK---ELLW--TAPELLRNMKLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVVVRGE 974
            :||.|...|.|   .|||  .:.::...:.|:..........:|.|...|:||.|.:.
Mouse   127 KGLLPDRVSRKVVPYLLWLLISAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFFITLP------- 184

  Fly   975 PYCMLSLSPEEIIVKIKKPPPLIRPSVSKGAAPP---EAINIMRQCWAEQPDMRPDFNSVY---- 1032
                |||||..||..:......:...|:......   |.:.::|:..|          :|:
Mouse   185 ----LSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILA----------NVFLYLC 235

  Fly  1033 ------ERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSV 1091
                  ..:.|.:...:..|::.. |.|| ...||||           :.::.|.|:..:||..|
Mouse   236 AIIVGIMSYYMADRKHRKAFLEAR-QSLE-VKMNLEE-----------QSQQQENLMLSILPKHV 287

  Fly  1092 AEKL-----KMGLAVDPEEFS--------DVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFD 1143
            |:::     |.....|.::|:        :|:|.|:||||||.:::.||..::|.|||:|:..||
Mouse   288 ADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFD 352

  Fly  1144 ATINAYNVYKVETIGDAYMVVSGLPVKIPDHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGL 1208
            .....|:..:::.:||.|..:.|||....|||.....|.|.::........|...||  .:|:|:
Mouse   353 KLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGV--DMRVGV 415

  Fly  1209 HTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPR----- 1268
            |||....||:|....:|.::...|..|::||:.|...|:|:||.|.|.|  :|.:.:||.
Mouse   416 HTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCL--KGEFDVEPGDGGSR 478

  Fly  1269 -GLIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGES--HGLDESLIRNSITLKAQANKSRTSTNP 1330
             ..:|.||   :.|:.::..|         |.:.::  :||:.|.:.|..              |
Mouse   479 CDYLDEKG---IETYLIIASK---------PEVKKTAQNGLNGSAVPNGA--------------P 517

  Fly  1331 SSSQSSSLAGESVEVKVEITPPTNADLASGTNLPNSYSLDSNSTNTISPNATLCPEFPGKTTPS- 1394
            :||:.||.|      .:|...|..:..|||:....:...::.:.|         |.||   .|.
Mouse   518 ASSKPSSPA------LIETKEPNGSAHASGSTSEEAEEQEAQADN---------PSFP---NPRR 564

  Fly  1395 ------------STSPQSRKLSELTPENLLNPNS 1416
                        ..|....:|::|..|.||...|
Mouse   565 RLRLQDLADRVVDASEDEHELNQLLNEALLERES 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	28/143 (20%)
		CYCc	1074..1266	CDD:214485	64/204 (31%)
Adcy3	NP_612178.2	AC_N	<44..303	CDD:318454	43/209 (21%)
		Guanylate_cyc	310..494	CDD:306677	61/190 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	504..564		20/91 (22%)
		Guanylate_cyc	915..1122	CDD:306677

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900