DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34357 and LOC101732945

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	XP_031761012.1	Gene:	LOC101732945 / 101732945	-ID:	-	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	533	Identity:	210/533 - (39%)
Similarity:	296/533 - (55%)	Gaps:	76/533 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   786 NGDLVQLKEV---NINGSAELRTKAMDLLVMAHGLRHENINPLIGWLSDPNRTAMVFDYCSRGSL 847
            :|.:|.:|::   ....|..:|.:...:    ..|.|.|:...||...:....|::.:||.:|||
Frog   212 DGRIVAIKKIQKKTFTLSKTIRREVKQI----RDLDHPNLCKFIGGCIEVPNVALITEYCPKGSL 272

  Fly   848 QDVLIMDEIKLDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFY 912
            .|||:.::|.|:|.||.|...|:.:||.|||...: .|..|.|.|||:|.|||.|||||||.::.
Frog   273 NDVLLSEDIPLNWGFRFSFAYDIAQGMAYLHQHRM-YHYRLKSTNCVIDDRWVCKITDYGLYTYR 336

  Fly   913 ESQG-----------LPPRTRSAKELLWTAPELLRNMKLHQHHHQHGRIQLGTQLGDVYSFGIIM 966
            ::..           :||...:.     :.||                   .:...|:||:.||:
Frog   337 KADTNVYQERLVQVYMPPEDETV-----SGPE-------------------KSAAADMYSYAIIL 377

  Fly   967 QEVVVRGEP----------YCMLSLSPEEIIVKIKKPPPLIRPSVSKGA-APPEAINIMRQCWAE 1020
            .|:..|.:|          :|.|.|            |.||:.....|. .|.|.:.::|:|.::
Frog   378 LEIATRNDPVPKDESGSAEHCCLPL------------PELIKGKSDNGCPCPSEYVELIRRCRSQ 430

  Fly  1021 QPDMRPDFNSVYER-FKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLN 1084
            .|..||.|..|.:: :||..|  ||:.||.|..::||||.:||:|:.|||:.|..|::||::||.
Frog   431 NPVQRPTFEQVKKQLYKMNPH--KVSPVDLMMTLMEKYSKHLEQLVAERTQDLMHEKQKTDRLLY 493

  Fly  1085 RMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAY 1149
            .|||..||:.|:.|.....:.::..||:||||||||.:::..:|.||||.||.|||.||..|:.|
Frog   494 SMLPKQVADDLRQGKPSQAQSYASATIFFSDIVGFTHLSSSSTPYQVVDFLNKLYTTFDDIIDNY 558

  Fly  1150 NVYKVETIGDAYMVVSGLP----VKIPDHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHT 1210
            :||||||||||||||||:|    ::   |..:||:|||||:.....|.:.|.|...|::|.|:|:
Frog   559 DVYKVETIGDAYMVVSGVPKENGIR---HVSEIASMALDLVSVCKTFRIPHKPNTQLKIRAGIHS 620

  Fly  1211 GPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKG 1275
            |...|||||..||||||||||||||||||||..:.:|..|..|.|.|...|||.:..||.:.:||
Frog   621 GSVVAGVVGTKMPRYCLFGDTVNTASRMESTSEALKIQCSSSTHDLLKQIGGYILVCRGTLQVKG 685

  Fly  1276 KGMMNTFWLLGKK 1288
            ||.|.|:||.|||
Frog   686 KGDMTTYWLEGKK 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	78/280 (28%)
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	102/195 (52%)
LOC101732945	XP_031761012.1	PKc_like	212..448	CDD:419665	76/276 (28%)
		HNOBA	<448..504	CDD:400168	28/57 (49%)
		CYCc	484..674	CDD:214485	101/192 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010