Protein Alignment CG34357 and gucy2c

DIOPT Version :9

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: XP_002934756.1
• Gene: gucy2c / 100486678
• XenbaseID: XB-GENE-952210
• Length: 1064
• Species: Xenopus tropicalis
• Alignment Length: 1113
• Identity: 328/1113 - (29%)
• Similarity: 489/1113 - (43%)
• Gaps: 298/1113 - (26%)

  Fly   317 LALDFNKTV--VLWPCPRMKISSNFLPSFEAISLAVQSISTKLNWSQVDIYIGDDN-----WGLG 374
            |:.|:::.:  :|.|..:|.........||.:      |..| .|..|.||..|.|     |.:.
 Frog   144 LSCDYHRYLARILLPARKMTYFFKEFWQFEGV------IKPK-KWQSVYIYKKDGNTESCFWYIN 201

  Fly   375 LAIAANLHVPY------RIEIGRTIRDLHS--QDKPGKAIIITAPLNDASTILLLSTIELDWTEQ 431
               |.:..|.|      ..||.||..:|..  |||....:||..
 Frog   202 ---ALDTGVSYFNSALNFKEILRTEAELLKVLQDKRKSNVIIMC--------------------- 242

  Fly   432 ARKDGQGSRPGRQHTKILL-IDMAASSLDT-QHGFYKYLSRMGGSQSDAFARN----TGSPAEV- 489
                |:.|.....|.|:.: .||....:|. ..|:|      ....|..:.:|    |..|:.:
 Frog   243 ----GRPSDIWNLHNKVAIPQDMVFILIDIFNTGYY------DNKSSHHYMQNVLVVTIRPSHMS 297

  Fly   490 -VSSNLLVLTLLNDRHRL-FLNAAGLMA-TMQNF-RAPLNGNYKDP------------------- 531
             :|:...:..:|.|.:.: :|:...|.. |::.| ::|   :.|:|
 Frog   298 KLSNTTGIAKILVDDYAVGYLDGVLLFGHTLKKFLKSP---DIKEPFSFIDQFRNISIIGAMGPL 359

  Fly   532 --PPSGHRNASLHKLYP------YRNLLPLYDTIVTTTTQSDTSETSPQFDFVVLDIVRDAPVAT 588
              ...|.|:.:|..:|.      |..|:. :||....||              |:|.|
 Frog   360 ILDEVGDRDLNLTLIYSSTATNNYTELIQ-FDTRTNKTT--------------VMDAV------- 402

  Fly   589 YKWRPLLI-----LESDPGSRGGGSVVEGGGSYISHSIHPGYDEWLLVSSVLLWQCGAICWTIAA 648
                |.||     |.||         |...|.:|                          .|||.
 Frog   403 ----PNLIWKNHRLPSD---------VPQSGPHI--------------------------LTIAV 428

  Fly   649 ICVCLLVIMIAGIVAGGIAMRNYFLRKRLSK------GPNKIV---LSASDFVFPVDSRRVDEGI 704
            ..:.::||::  ::.|.:..|.|.|...|.:      .|.||:   ::.:..|    |.::|:
 Frog   429 FTLTVVVILV--LITGLLVFRRYRLENELRQKKWSHISPEKILPLNMTETSHV----SLKIDD-- 485

  Fly   705 EAMLCCWLQQLQEFGGPEVDKPDLLKGSIGSLKNLGFVIPGAAAPGSAGAITTTANGKSGSSATG 769
                               ||
 Frog   486 -------------------DK-------------------------------------------- 487

  Fly   770 SLARHNPAHLDMRARYNGDLVQLKEVNINGSAELRTKAMDLLVMAHGLRHENINPLIGWLSDPNR 834
              .|.:...|.:| :|:..:|.||::..:|:...:.| |:|..:.. :.:.|:....|.:...|.
 Frog   488 --RRDSGPRLQIR-KYDKKVVILKDLKHDGNFTEKQK-MELNKLLQ-IDYYNLTKFYGTVKLDNI 547

  Fly   835 TAMVFDYCSRGSLQDVLIMDEIK------LDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNC 893
            ...|.:||.:|||:||| .|.|.      :||.|::|::.|:.:||.|||.|...|||.|.|.||
 Frog   548 IYAVIEYCDKGSLRDVL-NDNISYPDGTFMDWEFKISVMYDIAKGMSYLHASKSEVHGRLKSTNC 611

  Fly   894 VVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLRNMKLHQHHHQHGRIQLGTQLGD 958
            |||.|.|:||||:...|....|         |: ||::||.||         |.|    .:|.||
 Frog   612 VVDGRMVVKITDFAGKSILSPQ---------KD-LWSSPEHLR---------QEG----FSQKGD 653

  Fly   959 VYSFGIIMQEVVVRGEP-YCMLSLSPEEIIVKIK--KPPPLIRPSVSKGAAPPEAINI---MRQC 1017
            |||:|:|.||:::|.|. |.......:|.|.:::  |.....||.::...|....|.:   ::.|
 Frog   654 VYSYGVIAQEIMLRKETFYTEQCDDTKEKISRVQNYKGACPFRPDLNLDTANEREIEVYVLVKSC 718

  Fly  1018 WAEQPDMRPDF----NSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKK 1078
            |.|.|:.||||    |::.:.|...:.....:::||:.:.|:.||.|||.|:.|||:....||.:
 Frog   719 WEEDPERRPDFKKIENTLSKIFSNFHSQTTESYMDTLIRRLQLYSKNLEHLVEERTQLYKAERDR 783

  Fly  1079 TEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFD 1143
            .::|...:||..|...||....|:||.|.:||||||||||||||..:.:|::|||:|||:|..||
 Frog   784 ADRLNYLLLPGPVVMSLKETGRVEPEFFEEVTIYFSDIVGFTTICKYSAPMEVVDMLNDMYKNFD 848

  Fly  1144 ATINAYNVYKVETIGDAYMVVSGLPVKI-PDHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIG 1207
            ..::.::||||||||||||||||||.:. .:||..|:.||||:|...|.|.::||||:|:.:|||
 Frog   849 HILDHHDVYKVETIGDAYMVVSGLPNRNGNNHAVDISRMALDILCFMGSFELRHLPGLPVWIRIG 913

  Fly  1208 LHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQET---RDRLDARGGYAIEPRG 1269
            :|:|.|.|||||:.|||||||||||||||||||||...|||:::.|   ..|.|....|  |.||
 Frog   914 IHSGSCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVNKSTISILKRTDCEFRY--EVRG 976

  Fly  1270 LIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGESHGLDE---SLIRNSITLK-AQANKSRTSTNP 1330
            ...:||||...|:||.|:......:|.||.:.....|..   .:|..|:..| |...|::..|..
 Frog   977 ETYLKGKGTETTYWLTGETEQKYNIPTPPSVENQQRLQSDFAEMIMESLKRKEADGYKNKEPTRV 1041

  Fly  1331 SSSQSSSL 1338
            :|.::.:|
 Frog  1042 ASYRNGTL 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	93/293 (32%)
		CYCc	1074..1266	CDD:214485	108/195 (55%)
gucy2c	XP_002934756.1	Periplasmic_Binding_Protein_Type_1	29..407	CDD:299141	67/332 (20%)
		PKc_like	472..741	CDD:304357	97/366 (27%)
		Pkinase	497..732	CDD:278497	89/261 (34%)
		CYCc	779..971	CDD:214485	107/191 (56%)
		Guanylate_cyc	806..993	CDD:278633	110/188 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	235	1.000	Domainoid score	I2306
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010