DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34357 and gucy1b1

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	XP_004911214.1	Gene:	gucy1b1 / 100379900	XenbaseID:	XB-GENE-950986	Length:	618	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	113/301 - (37%)
Similarity:	167/301 - (55%)	Gaps:	27/301 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly  1008 PEAINIMRQCWAEQPDMRPDFNSVYERFKMLN----HGRKVNFVDTMFQMLEKYSNNLE-ELIRE 1067
            |||.||:..|   .|.:. :.:.:..|...|:    |....:.|....|..|:|....| |::.:
Frog   314 PEADNILFLC---SPSVM-NLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTD 374

  Fly  1068 RTEQ----LDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAA-HCS 1127
            |.:.    |:.|:|||:.||..:||.|||.:|:....|..:.:.:|||.||.||||.|..: |.|
Frog   375 RLQHTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHAS 439

  Fly  1128 ---PVQVVDLLNDLYTIFDATINAYN---VYKVETIGDAYMVVSGLPVKIPDHAEQIATMALDLL 1186
               .:::|:||||:||.||...::.|   ||||||:||.||.|||:|.....||..|..:|||::
Frog   440 GEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMM 504

  Fly  1187 HQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQ 1251
            ..:|:..|   .|..:|:.||:|||....||:|..||||||||:|||..||.|:||...:|::|:
Frog   505 EIAGQVQV---DGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSE 566

  Fly  1252 ETRDRL----DARGGYAIEPRGLIDIKGKGMMNTFWLLGKK 1288
            .|...|    ::...:.::.||.:.:|||......|.|.:|
Frog   567 YTYRCLMSPENSDPQFHLQYRGPVSMKGKTDPMQVWFLSRK 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	9/36 (25%)
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	87/202 (43%)
gucy1b1	XP_004911214.1	HNOB	2..166	CDD:377902
		HNOBA	207..406	CDD:369471	29/95 (31%)
		Guanylate_cyc	412..605	CDD:306677	81/195 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910