Protein Alignment CG34357 and gucy1b1

DIOPT Version :10

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: XP_004911214.1
• Gene: gucy1b1 / 100379900
• XenbaseID: XB-GENE-950986
• Length: 618
• Species: Xenopus tropicalis
• Alignment Length: 301
• Identity: 113/301 - (37%)
• Similarity: 167/301 - (55%)
• Gaps: 27/301 - (8%)

  Fly  1008 PEAINIMRQCWAEQPDMRPDFNSVYERFKMLN----HGRKVNFVDTMFQMLEKYSNNLE-ELIRE 1067
            |||.||:..|   .|.:. :.:.:..|...|:    |....:.|....|..|:|....| |::.:
 Frog   314 PEADNILFLC---SPSVM-NLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTD 374

  Fly  1068 RTEQ----LDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAA-HCS 1127
            |.:.    |:.|:|||:.||..:||.|||.:|:....|..:.:.:|||.||.||||.|..: |.|
 Frog   375 RLQHTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHAS 439

  Fly  1128 ---PVQVVDLLNDLYTIFDATINAYN---VYKVETIGDAYMVVSGLPVKIPDHAEQIATMALDLL 1186
               .:::|:||||:||.||...::.|   ||||||:||.||.|||:|.....||..|..:|||::
 Frog   440 GEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMM 504

  Fly  1187 HQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQ 1251
            ..:|:..|   .|..:|:.||:|||....||:|..||||||||:|||..||.|:||...:|::|:
 Frog   505 EIAGQVQV---DGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSE 566

  Fly  1252 ETRDRL----DARGGYAIEPRGLIDIKGKGMMNTFWLLGKK 1288
            .|...|    ::...:.::.||.:.:|||......|.|.:|
 Frog   567 YTYRCLMSPENSDPQFHLQYRGPVSMKGKTDPMQVWFLSRK 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	Protein Kinases, catalytic domain	763..1041	CDD:473864	9/36 (25%)
		HNOBA	<1047..1095	CDD:462234	19/52 (37%)
		CYCc	1074..1266	CDD:214485	87/202 (43%)
gucy1b1	XP_004911214.1	HNOB	2..166	CDD:462233
		HNOBA	207..406	CDD:462234	29/95 (31%)
		Guanylate_cyc	412..605	CDD:425528	81/195 (42%)