Protein Alignment CG34357 and gucy1b1

DIOPT Version :10

• Sequence 1: NP_001356914.1
• Gene: CG34357 / 5740349
• FlyBaseID: FBgn0085386
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: NP_001238874.1
• Gene: gucy1b1 / 100150304
• ZFINID: ZDB-GENE-090313-160
• Length: 608
• Species: Danio rerio
• Alignment Length: 302
• Identity: 115/302 - (38%)
• Similarity: 167/302 - (55%)
• Gaps: 29/302 - (9%)

  Fly  1008 PEAINIMRQCWAEQPDMRPDFNSVYERFKMLN----HGRKVNFVDTMFQMLEKYSNNLE-ELIRE 1067
            ||..||:..|   .|.:. :.:.:..|...|:    |....:.|....|..|:|....| |::.:
Zfish   314 PETENILFLC---SPSVM-NLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTD 374

  Fly  1068 RTEQ----LDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAA-HCS 1127
            |.:.    |:.|:|||::||..:||.|||.:|:....|..:.:.:|||.||.||||....: |.|
Zfish   375 RLQHTLRALEDEKKKTDRLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHAS 439

  Fly  1128 ---PVQVVDLLNDLYTIF----DATINAYNVYKVETIGDAYMVVSGLPVKIPDHAEQIATMALDL 1185
               .:::|:||||:||.|    |:..|.| ||||||:||.||.|||||.....||:.|..:|||:
Zfish   440 AEGAIKIVNLLNDIYTRFDILTDSRKNPY-VYKVETVGDKYMTVSGLPEPCTHHAKSICHLALDM 503

  Fly  1186 LHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMS 1250
            :..:|:..|..   .|:|:.||:|||....||:|..||||||||:|||..||.|:||...:|::|
Zfish   504 MEIAGQVKVDE---DPVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVS 565

  Fly  1251 QETRDRL----DARGGYAIEPRGLIDIKGKGMMNTFWLLGKK 1288
            :.|...|    :|...:.:|.||.:.:|||......|.|.:|
Zfish   566 EYTYRCLQSVENADPQFHLEYRGPVTMKGKKEPMKVWFLSRK 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	Protein Kinases, catalytic domain	763..1041	CDD:473864	8/36 (22%)
		HNOBA	<1047..1095	CDD:462234	19/52 (37%)
		CYCc	1074..1266	CDD:214485	89/203 (44%)
gucy1b1	NP_001238874.1	HNOB	2..166	CDD:462233
		HNOBA	207..406	CDD:462234	28/95 (29%)
		Guanylate_cyc	412..605	CDD:425528	84/196 (43%)