DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34357 and adcy7

DIOPT Version :9

Sequence 1:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster
Sequence 2:	NP_001106549.1	Gene:	adcy7 / 100127741	XenbaseID:	XB-GENE-1005225	Length:	1061	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	95/377 - (25%)
Similarity:	167/377 - (44%)	Gaps:	80/377 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1071 QLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSD------------------VTIYFSDIV 1117
            :|::::::.|.||..:||..::.::|:.:.....|.:|                  |:|.::|||
Frog   220 KLELKKRQQESLLLSVLPVYISMEMKLAIQDRLTETNDNRQPDNNFHSLYVKRHQNVSILYADIV 284

  Fly  1118 GFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIPDHAEQIATMA 1182
            |||.:|:.|||.::|.:||:|:..||.........:::.:||.|..||||||.:|::|:....|.
Frog   285 GFTRLASDCSPKELVVMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPVSLPNNAKNCVKMG 349

  Fly  1183 LDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRI 1247
            ||:.....:  |:...|..:.:|:|:|:|....||:||...::.::...|:.|:||||.|...|:
Frog   350 LDICEAIKQ--VREATGADINMRVGVHSGNVLCGVIGLRKWQFDVWSHDVSLANRMESAGLPGRV 412

  Fly  1248 HMSQETRDRLDARGGYAIEPRGLIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGESHG------L 1306
            |:::.|...::  |.|.:|                                   |.||      |
Frog   413 HITEATLKHMN--GAYDVE-----------------------------------EGHGELRDPYL 440

  Fly  1307 DESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEITPPTNAD--LAS-GTNLPNSY- 1367
            .|..|:..:.:..:|..||...|       .|....|...:::.|.....  |.| |...|.|:
Frog   441 KEMNIKTFLVIDPRAKNSRVKNN-------HLTRHRVNDGIKVRPSVRMTRYLESWGAARPFSHF 498

  Fly  1368 -SLDSNSTNTISPNATLCPEFP----GKTTPSSTS-PQSRKLSELTPENLLN 1413
             ..|::||...:.|....||.|    |:|..:..: .|.|...|...:.::|
Frog   499 DQTDASSTEVPTVNGKPKPEIPLKGMGRTVKTERNVSQKRNQEEELHDRMMN 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	62/209 (30%)
adcy7	NP_001106549.1	AC_N	<21..266	CDD:318454	9/45 (20%)
		Guanylate_cyc	268..418	CDD:306677	51/151 (34%)
		DUF1053	483..591	CDD:399378	18/68 (26%)
		Guanylate_cyc	851..1048	CDD:306677
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910