Protein Alignment smal and ddr2a

DIOPT Version :10

• Sequence 1: NP_723165.2
• Gene: smal / 5740323
• FlyBaseID: FBgn0085409
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: XP_005166320.1
• Gene: ddr2a / 556380
• ZFINID: ZDB-GENE-090316-2
• Length: 868
• Species: Danio rerio
• Alignment Length: 630
• Identity: 185/630 - (29%)
• Similarity: 277/630 - (43%)
• Gaps: 112/630 - (17%)

  Fly    40 PRPPCRAPRWTLCLWTLVIASGCLMLNAPTTMAFDIATCNVPLGMESLLITDAQITASSAHDMAF 104
            |.|......|.:....|::    |.|:.......:...|..||||....|.|..|:|||....:
Zfish     4 PSPTEMKQLWKMHFPLLIL----LYLSGAVQSQVNPGVCRSPLGMSRGQILDEDISASSQWSES- 63

  Fly   105 VGPQHARLKTDNDGGAWCPKHMVS-NALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVL 168
            ...::.||..:...|||||:.... ..:||:||:||...|.||.:.||||:..|.|.|:.:.|.:
Zfish    64 TAAKYGRLDCEEGDGAWCPEIPAEPENMKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQTYKI 128

  Fly   169 EYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVG 233
            :|.|.| .:|..|:|.||||::.||.|.|..|...|:|.|.|..:|..|...:...||:|.|:.|
Zfish   129 KYSRDG-SRWISWRNRQGKEVIEGNRNAYDIVLKDLEPPIIARFVRFMPVIDHSMNVCMRVELYG 192

  Fly   234 CPWEEGIVSYSIPKGVQ---RGMEVDLSDKTYDGNEQGDRYVDGLGQLVDGQKGKDNFR-TDIHG 294
            |.|.:|:|||:.|.|.|   .|..:.|:|..||| .......:|||||.||..|.|:|. :.::.
Zfish   193 CEWLDGLVSYNSPLGQQMSLNGQHIYLNDSVYDG-AMSYSMTEGLGQLTDGMCGLDDFTLSHVYN 256

  Fly   295 FGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRY 359
            ...||:::||.|::  .....|||:||||..|||:.:.:|.||||::.|:.|  .||..     |
Zfish   257 VWPGYDYVGWTNES--FPNGYVEIMFEFDRTRNFTTMKVHCNNMFSRRVKTF--QKVVC-----Y 312

  Fly   360 FSGE------PVQFSYMPDTIMDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPAMG 418
            |..|      ||.||.:.|.:...||.||:.|::.:...:|...||:..|:|.|||:|.|..||.
Zfish   313 FRSELDWEATPVSFSPVMDDVNPSARFVTVSLYNHMASAIKCQYYFSDIWMMFSEITFQSDTAMY 377

  Fly   419 NFTDEQEQRSNSPSQAQDVHDETNGSEYQANRNKPNGVGGSAGGLGEGVAAAGGDIVGNNKYNNG 483
            | |.....|::.|...|...|.|:
Zfish   378 N-TTLTPPRTDPPLTNQPGDDPTH----------------------------------------- 400

  Fly   484 PQLIAPRPIDQEPNDANFIGVVIVVLTTIIILLVAIILFIVSR-------TKRAR--------GS 533
                       :.:|:| ..::|..|..||.:|||||:.|:.|       .|.:|        .|
Zfish   401 -----------KVDDSN-TRILIGCLVAIIFILVAIIVIILWRQVWQKMLEKVSRRMLDDELTAS 453

  Fly   534 NVLDAFQYSFNPNTLGGNVDKHRPNGNSIKANVDDNDSIGKNSLYHEPFNV--NMYTCGVNGYAA 596
            ..:.:..:::|.|....:|    |:.....:..:....:|.:  |.||..:  .:..........
Zfish   454 LSIQSETFTYNNNNSPSSV----PSEQESSSTYERIFPLGPD--YQEPSRLVRKLPEFSQTSEDT 512

  Fly   597 VNDLQCNMTPDYTDVPEGGYAVPHMQDYMPSSKMG-GGAPGGGGY 640
            .:.:..:.||. .:|.||   |||   |..:..:. .|..||..|
Zfish   513 ASTITASKTPS-VNVQEG---VPH---YAEADIVNLQGVTGGNTY 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smal	NP_723165.2	FA58C	81..233	CDD:238014	59/152 (39%)
ddr2a	XP_005166320.1	FA58C	40..192	CDD:238014	59/153 (39%)
		Protein Kinases, catalytic domain	569..865	CDD:473864