DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment smal and Alk

DIOPT Version :9

Sequence 1:	NP_723165.2	Gene:	smal / 5740323	FlyBaseID:	FBgn0085409	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_001261027.1	Gene:	Alk / 53425	FlyBaseID:	FBgn0040505	Length:	1701	Species:	Drosophila melanogaster

Alignment Length:	233	Identity:	44/233 - (18%)
Similarity:	77/233 - (33%)	Gaps:	105/233 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   442 NGSEYQANRNKPNGVGGSAGGL---GEGVAAAGGDIV-------GNNKY---------------- 480
            ||:  ..:|:...|.||..||.   |.|...||||:.       |.:.|
  Fly   978 NGT--SVHRHGQGGFGGGGGGCNTGGGGGGYAGGDVYLTESNGEGGSSYISPSRSLREISEIHAG 1040

  Fly   481 -NNGPQLIAPRP----------------------------------------IDQEPNDANF--- 501
             ::||..|...|                                        |.:|...::|
  Fly  1041 ASSGPGAIIIIPAIEGCGCDYRCVALDEFRSKVRCICPDGWSLKRDNHTACEIREEAGKSSFQYL 1105

  Fly   502 IGVVIVVLTTIIILLVAIILFIVSRTKRARGS-------------------NVLDAFQYSFNPN- 546
            :.::::.|..:.|.:.|:|..:.:|.:|.:.|                   |:.|:...:||||
  Fly  1106 VSILMISLAVLFICIAALIFMLYNRYQRKKQSKKRHKMLVEQDLQLTRLRNNIDDSNLNNFNPNY 1170

  Fly   547 ----TLGGNVDKHRPNGNSIKANVDDN----DSIGKNS 576
                .|.|::|.     ||:.....|:    :::||.:
  Fly  1171 GCDGILNGHIDV-----NSLPQVARDSLQLVNALGKGA 1203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smal	NP_723165.2	FA58C	78..234	CDD:214572
smal	NP_723165.2	FA58C	81..233	CDD:238014
Alk	NP_001261027.1	MAM	288..450	CDD:279023
		MAM	288..447	CDD:99706
		MAM	505..691	CDD:279023
		MAM	505..689	CDD:99706
		PTKc_ALK_LTK	1186..1462	CDD:270632	3/18 (17%)
		TyrKc	1193..1460	CDD:197581	2/11 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010