Protein Alignment smal and Ddr

DIOPT Version :10

• Sequence 1: NP_723165.2
• Gene: smal / 5740323
• FlyBaseID: FBgn0085409
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Alignment Length: 770
• Identity: 410/770 - (53%)
• Similarity: 503/770 - (65%)
• Gaps: 130/770 - (16%)

  Fly    16 SMFSR-QCLSHLTRSPPTTTPTAAAP--------------RPP-------CRAPRW------TLC 52
            |::|| :|           :||...|              ||.       ||..|.      |||
  Fly    11 SIYSRSEC-----------SPTIGVPALVESQGGEGHESRRPATNYLKSYCRIKRHGVNNSKTLC 64

  Fly    53 LWTLVIASGCLMLN---------APTTMA----------FDIATCNVPLGMESLLITDAQITASS 98
            ..||.:   .|:.|         .|.|.|          ..|.||...|||||..|.|.||||||
  Fly    65 WLTLTL---ILLANRFGMGTAVGTPETPAAVGSNGLLAEMPIGTCKQALGMESGAIADFQITASS 126

  Fly    99 AHDMAFVGPQHARLKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYT 163
            ||||..|||||||||.||:|||||||||||..|.||||||||..|:::|||||||:|||||||||
  Fly   127 AHDMGNVGPQHARLKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYT 191

  Fly   164 EAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLR 228
            ||||:||||||..||.||:::||||:|||||||||||||.|||.:||||:|:|||.|||||||||
  Fly   192 EAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLR 256

  Fly   229 AEIVGCPWEEGIVSYSIPKGVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLVDGQKGKDNFRTDIH 293
            ||||||.|||||||||||||:||||::|||||||||.|:||.||:|||||||||:||||||.||:
  Fly   257 AEIVGCAWEEGIVSYSIPKGMQRGMDIDLSDKTYDGYEEGDHYVNGLGQLVDGQRGKDNFRADIN 321

  Fly   294 GFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGR 358
            |.|||||||||||||  |||:||||:|||:||||.||:::||||||:||||||||||||||||||
  Fly   322 GLGKGYEWIGWRNDT--LLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGR 384

  Fly   359 YFSGEPVQFSYMPDTIMDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPAMGNFTDE 423
            :|||||||||||||.::|||||||||||||:|:|::::||||.:|:|:|||:|||.|.:||||||
  Fly   385 HFSGEPVQFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPVVGNFTDE 449

  Fly   424 QEQRSNSPSQAQDVHDETNGSEYQANRNKPNGVGGSAGGLGEGVAAAGGDIVGNNKYNNGPQLIA 488
               .:|...|:..       |||...|::          :|..:::      |..:..:..|:|:
  Fly   450 ---LANGEKQSVT-------SEYPLQRDE----------VGRAISS------GGERSQHTTQVIS 488

  Fly   489 PRPIDQEPNDANFIGVVIVVLTTIIILLVAIILFIVSRTKRARG-SNVLDAFQYSFNPNTLGGN- 551
            |:|||.:..:.:|:||:|.||.|||:||||.||.||:|.|..|. .|.|||||::|:|:||.||
  Fly   489 PKPIDHQEPETSFVGVIITVLGTIIMLLVAFILLIVARNKHVRSRENGLDAFQHNFSPDTLNGNG 553

  Fly   552 VDKHRPNGNSIKANVDDND-SIGKNSLYHEPFNVNMYTCGVNGYAAVNDLQ-CNMTPDYTDVPE- 613
            |.|       :...:|||: ||.||||||||||.||||...:. ..:|||| .:::|||||||:
  Fly   554 VLK-------VVTTMDDNESSIDKNSLYHEPFNANMYTSAASA-CPMNDLQRQHVSPDYTDVPDI 610

  Fly   614 --GGYAVPHMQDYMPSSKMGGGAPGGGGYVNVRRTPPPPL----------------SSIFPRPPT 660
              ..|||||||..:|::...|...|.|......|...|..                ::..|.|..
  Fly   611 VCQDYAVPHMQQLLPNAPPCGSGCGTGTGTGPGRGSSPEFVVATGKVTASARNSLNAATLPLPSP 675

  Fly   661 VPPPPMEKYYATTAIFK---PLKGPGSERSGCSSNTNTVSS-------GGGKSSH 705
            ..|||:|||||.|.:..   |:..|||:.||..|::.|.::       |.||..|
  Fly   676 PVPPPLEKYYAATPVSSKPMPVAPPGSQSSGSLSSSTTAATTPTSGVVGVGKPHH 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smal	NP_723165.2	FA58C	81..233	CDD:238014	119/151 (79%)
Ddr	NP_001014474.3	FA58C	109..261	CDD:238014	119/151 (79%)
		PTKc_DDR	753..1040	CDD:270644