Protein Alignment smal and Ddr2

DIOPT Version :9

• Sequence 1: NP_723165.2
• Gene: smal / 5740323
• FlyBaseID: FBgn0085409
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: XP_036018652.1
• Gene: Ddr2 / 18214
• MGIID: 1345277
• Length: 864
• Species: Mus musculus
• Alignment Length: 697
• Identity: 194/697 - (27%)
• Similarity: 281/697 - (40%)
• Gaps: 195/697 - (27%)

  Fly    26 LTRSPPTTTPTAAAPRPPCRAPRWTLCLWTLVIASGCLMLNAPTTMAFDIATCNVPLGMESLLIT 90
            :|..|..::.....||.|.     .|.|..|::.|....:|.        |.|..||||....|.
Mouse     1 MTPDPTPSSEMIPIPRMPL-----VLLLLLLILGSAKAQVNP--------AICRYPLGMSGGHIP 52

  Fly    91 DAQITASSAHDMAFVGPQHARLKTDNDGGAWCPKHMVS-NALKEYLQVDLLQTHVITAIRTQGRY 154
            |..|||||....: ...::.||.::...|||||:..|. :.|||:||:||...|.||.:.||||:
Mouse    53 DEDITASSQWSES-TAAKYGRLDSEEGDGAWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRH 116

  Fly   155 GKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYG 219
            ..|.|.|:...|.:.|.|.| .:|..|:|..||::|.||.|.|......|:|.|.|..:|:.|..
Mouse   117 AGGHGIEFAPMYKINYSRDG-SRWISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVT 180

  Fly   220 QYDRTVCLRAEIVGCPWEEGIVSYSIPKGVQ----RGMEVDLSDKTYDGNEQGDRYVDGLGQLVD 280
            .:...||:|.|:.||.|.:|:|||:.|.|.|    .|..:.|:|..||| ..|....:|||||.|
Mouse   181 DHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTD 244

  Fly   281 GQKGKDNFRTDIHGF--GKGYEWIGWRND--TPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTK 341
            |..|.|:| |..|.:  ..||:::||||:  |.|.    :||:||||.:|||:.:.:|.||||.|
Mouse   245 GVSGLDDF-TQTHEYHVWPGYDYVGWRNESATNGF----IEIMFEFDRIRNFTTMKVHCNNMFAK 304

  Fly   342 DVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDTIMDHARDVTIKLHHRVGKYLKINLYFAVKWIML 406
            .|::|...:.:|......:....|.|..:.|.:...||.||:.||||:...:|...:||..|:|.
Mouse   305 GVKIFKEVQCYFRSEASEWEPTAVYFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMF 369

  Fly   407 SEISFISVPAMGNFTDEQEQRSNSPSQAQDVHDETNGSEYQANRNKPNGVGGSAGGLGEGVAAAG 471
            |||:|.|..||
Mouse   370 SEITFQSDAAM------------------------------------------------------ 380

  Fly   472 GDIVGNNKYNNGPQL----IAPRPIDQ--EPNDANFIGVVIVVLTTIIILLVAIILFIVSR---- 526
                    |||...|    :||...|.  :.:|:| ..::|..|..||.:|:|||:.|:.|
Mouse   381 --------YNNSGALPTSPMAPTTYDPMLKVDDSN-TRILIGCLVAIIFILLAIIVIILWRQFWQ 436

  Fly   527 ---TKRARGSNVLDAFQYSFNPNTLGGNVDKHRPNGNSIKANVDDNDSIGKNSLYHEPFNVNMYT 588
               .|.:|  .:||                    :..::..::....|:..|:....|
Mouse   437 KMLEKASR--RMLD--------------------DEMTVSLSLPSESSMFNNNRSSSP------- 472

  Fly   589 CGVNGYAAVNDLQCNMTPDYTDVPEGGYAVPHMQDYMPSSKMGGGAPGGGGYVNVRRTPPPPLSS 653
                     ::.:.|.|.|        ...|...||...|::            :|:.|.
Mouse   473 ---------SEQESNSTYD--------RIFPLRPDYQEPSRL------------IRKLPE----- 503

  Fly   654 IFPRPPTVPPPPMEKYYATTAIFKPLKGPGSERSGCSSNTNTVSSGG 700
                            :|          ||.|.||||.........|
Mouse   504 ----------------FA----------PGEEESGCSGVVKPAQPNG 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smal	NP_723165.2	FA58C	78..234	CDD:214572	61/156 (39%)
		FA58C	81..233	CDD:238014	60/152 (39%)
Ddr2	XP_036018652.1	FA58C	42..194	CDD:238014	60/153 (39%)
		PKc_like	567..860	CDD:419665

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I6997
eggNOG	1	0.900	-	-		E1_KOG1094
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68505
Inparanoid	1	1.050	527	1.000	Inparanoid score	I1219
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001292
OrthoInspector	1	1.000	-	-		mtm8799
orthoMCL	1	0.900	-	-		OOG6_103661
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X998
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.820