Protein Alignment smal and ddr-1

DIOPT Version :9

• Sequence 1: NP_723165.2
• Gene: smal / 5740323
• FlyBaseID: FBgn0085409
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: NP_508926.2
• Gene: ddr-1 / 180817
• WormBaseID: WBGene00016104
• Length: 766
• Species: Caenorhabditis elegans
• Alignment Length: 627
• Identity: 173/627 - (27%)
• Similarity: 259/627 - (41%)
• Gaps: 184/627 - (29%)

  Fly    69 TTMAFDIATCNV-PLGMESLLITDAQITASSAHDMAFVGPQHARLKTDNDGGAWCPKHMVSNALK 132
            ||....|..|.. .|||::..|.|:||||||:.|...||||:|||.::...||||||..:::...
 Worm    15 TTNTLRIDQCGENALGMQNGDIADSQITASSSFDKQSVGPQNARLHSELASGAWCPKPQINSKSY 79

  Fly   133 EYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTY 197
            |:|||.|..|.:||::.||||||.|.|:|:...|:::|.||| .:|.|:||..|...:.||.:|.
 Worm    80 EFLQVTLNDTFLITSVETQGRYGNGTGREFASHYMIDYLRPG-SQWIRYKNRTGHVYMDGNFDTT 143

  Fly   198 SEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSYS-IPKGVQRGMEVDLSDKT 261
            :.|...|.|.|.||:||..|..:..||||:||||.||. .||:..|| :|.| .|...:|..|..
 Worm   144 TPVIRVLDPPIVASRIRFVPSSKNTRTVCMRAEIHGCK-HEGVTYYSTVPDG-SRLDTLDFKDSM 206

  Fly   262 YDGN----EQGDRYVDGLGQLVDGQKGKDNFRTDIHGFGKGY---EWIGWRNDTPGLLGKPVEIV 319
            ::.:    |.|.:  .|||.|.||      |......|.|..   .||||..||..  |: :.|:
 Worm   207 FEDSQIYTESGIK--RGLGLLTDG------FVAQASPFEKNQMNNSWIGWNRDTTD--GR-ITIL 260

  Fly   320 FEFDTVRNFSAIVLHT--NNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMP----DTIMDHA 378
            |||:.|.||:.:||.|  |.:...|        |.||..|:.|   |: ||.:.    .::.:.:
 Worm   261 FEFEEVHNFTDVVLATFGNRIDGID--------VIFSQDGKTF---PL-FSQISSSERQSLNNTS 313

  Fly   379 R--DVTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPAMGNFTDEQEQRSNSPSQAQDVHDET 441
            |  |..:.||:|.|:.::|::.|:..|:.|:|:.|.|...:...:::....|::.:|.
 Worm   314 RRYDFRVPLHNRAGRKVRISIKFSSDWMFLTEVHFTSAANLTLLSEKIPPPSSAATQQ------- 371

  Fly   442 NGSEYQANRNKPNGVGGSAGGLGEGVAAAGGDIVGNNKYNNGPQLIAPRPIDQEPNDANFIGVVI 506
                                                                           ::
 Worm   372 ---------------------------------------------------------------LL 373

  Fly   507 VVLTTIIILLVAIILFIVSRTKRARGSNVLDAFQYSFNPNTLGGNVDK--------HRPNGNSIK 563
            ||...|.:.:.|.:.:.||...:.|..|           .::..||.|        ::|..:...
 Worm   374 VVCGIIFLTIFACVAYCVSVCLKRRQKN-----------KSVDSNVKKDLIITHMGNKPTCHVFP 427

  Fly   564 ANVDDNDSIGKNSLYHEPFNVNMYTCGVNGYAAVNDL-------------------QCN-MTPDY 608
            :|       ||.|..|              |...||:                   .|. :.|.:
 Worm   428 SN-------GKLSNGH--------------YEVANDILYARSQKSTLLSVSSKSTFSCRAIPPTW 471

  Fly   609 TDV-----PEGGYAVPHMQDYMPSSKMGGGAPGGGGYVNVRR 645
            ||.     |||.....:.|...|.:.      ..|.|.:||:
 Worm   472 TDFNFPPPPEGREEHTYSQPVSPENS------SNGSYKSVRK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smal	NP_723165.2	FA58C	78..234	CDD:214572	73/156 (47%)
		FA58C	81..233	CDD:238014	72/151 (48%)
ddr-1	NP_508926.2	FA58C	27..179	CDD:238014	72/152 (47%)
		FA58C	34..180	CDD:214572	69/146 (47%)
		Pkinase_Tyr	519..761	CDD:285015
		PKc_like	525..762	CDD:304357

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3139
eggNOG	1	0.900	-	-		E1_KOG1094
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I1772
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D122892at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4852
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R14052
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.860