Protein Alignment smal and ddr-2

DIOPT Version :9

• Sequence 1: NP_723165.2
• Gene: smal / 5740323
• FlyBaseID: FBgn0085409
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: NP_508572.1
• Gene: ddr-2 / 180622
• WormBaseID: WBGene00017381
• Length: 797
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 162/585 - (27%)
• Similarity: 263/585 - (44%)
• Gaps: 125/585 - (21%)

  Fly    69 TTMAFDIATCNVPLGMESLLITDAQITASSAHDMAFVGPQHARLKTDNDGGAWCPKHMVSNALKE 133
            |.:|.::..|:..|||.:..|.|.||:|||:.|:...||||||...::..||||||:.:::..||
 Worm    16 TVVALELRECSHQLGMSNRKIRDEQISASSSFDLQSTGPQHARAHQESGSGAWCPKNQINSLSKE 80

  Fly   134 YLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYS 198
            :||:......|||::.||||:..|:|.||..|:.::||||..:.|..:|:....|.:|.|.:|..
 Worm    81 WLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEH 145

  Fly   199 EVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSYSIPKG-VQRGMEVDLSDKTY 262
            .:...|...|.|.:|||.|.....||||:|.|:.|||:::.:|.|::.:| :|.|  :...|.:|
 Worm   146 AIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDLQSG--ISYHDFSY 208

  Fly   263 DGN-EQGDRYVDGLGQLVDGQKGKDNFRTDIHGFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVR 326
            ||| ........|:|:|.||:.||:|.      |...::|:|||....|    .|::.|||..:|
 Worm   209 DGNLANSPHLTGGIGKLYDGEVGKNNV------FVNHHKWVGWRRKRNG----NVKLAFEFSELR 263

  Fly   327 NFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDTIMDHARDVTIKLHHRVGK 391
            |.|.|::||:|.|.|..:.|..|.|.|||.|:.||...|.|:...||..:..|.:.|.:::|:.|
 Worm   264 NISGILIHTSNEFKKSAKAFSSATVLFSINGKDFSDTIVHFNNPEDTESEVPRWIRIPVNNRIAK 328

  Fly   392 YLKINLYFAV--KWIMLSEISFISVPAMGNFTDEQEQRSNSPSQAQDVHDETNGSEYQANRNKPN 454
            ..||.|.|..  .|:.:||::|.|                         :.||
 Worm   329 VAKIRLNFGTDSDWLFISEVNFES-------------------------NHTN------------ 356

  Fly   455 GVGGSAGGLGEGVAAAGGDIVGNNKYNNGPQLIAPRPIDQEPNDANFIGVVIVVLTTIIILLVAI 519
                        :.....|:|       .|..::...:.:..:..:....:|.....:|:.::.:
 Worm   357 ------------IELLNDDVV-------IPDSVSYFSVTEHDDGTSMFAFIIFFFMFLIVAVIIL 402

  Fly   520 ILFIVSRTKRARGSNVLDAFQYSFNPN-------TLGGNVDKHRPNGNSIKANVDD--NDSIGKN 575
            .:....|..|.:.|        |.:||       |:.||..||..:.::.:...|:  |..|.|.
 Worm   403 TVLYRKREYRVKAS--------SPSPNAKREILLTIDGNTIKHHVSPSTYQMARDNLQNALIEKM 459

  Fly   576 SL------YHEPFNVNMYTC-----------GVNG----------------YAAVNDLQCNMTPD 607
            .:      |.||   ::..|           |::|                |:...::.|...|:
 Worm   460 PMSPIISDYAEP---DISVCSDVTANTPLLYGIDGPYDTQKRSNPLSSMVKYSDYGEVYCTTLPE 521

  Fly   608  607
             Worm   522  521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smal	NP_723165.2	FA58C	78..234	CDD:214572	63/155 (41%)
		FA58C	81..233	CDD:238014	62/151 (41%)
ddr-2	NP_508572.1	FA58C	24..181	CDD:214572	63/156 (40%)
		FA58C	29..180	CDD:238014	62/150 (41%)
		PKc_like	521..787	CDD:304357	0/1 (0%)
		TyrKc	527..785	CDD:197581

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I4168
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68505
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D122892at33208
OrthoFinder	1	1.000	-	-		FOG0001292
OrthoInspector	1	1.000	-	-		mtm4852
orthoMCL	1	0.900	-	-		OOG6_103661
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X998
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.820