DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment uex and SPCC4B3.03c

DIOPT Version :9

Sequence 1:	NP_001104390.2	Gene:	uex / 5740320	FlyBaseID:	FBgn0262124	Length:	834	Species:	Drosophila melanogaster
Sequence 2:	NP_588087.1	Gene:	SPCC4B3.03c / 2538837	PomBaseID:	SPCC4B3.03c	Length:	679	Species:	Schizosaccharomyces pombe

Alignment Length:	415	Identity:	144/415 - (34%)
Similarity:	223/415 - (53%)	Gaps:	45/415 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 EVSSNGFSAL------YSVKFPSFINEFFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFE 181
            :.|..|||.:      |:|.:|  :..|         ..|........|.:..|.....|...||
pombe     8 KASLYGFSTVFILLQSYAVAYP--LRAF---------RQNDGIGIAMNPSQDGGFVSAEKDSDFE 61

  Fly   182 PLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQG-NY 245
                .|:.:||....:....:|:||.:|||..|...|::|..:|...|:.:|.|:..:..:| ::
pombe    62 ----YWMKLIISAVLILLGGVFAGLTIGLMGCDDLHLQVLEQSGDASERVHARKVLKLLRRGKHW 122

  Fly   246 LLCSILLGNVLVNSTFTILLDGLTSGLF-AVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVT 309
            :|.::|||||:||.|..|:.|.:..|.: ||:.||..||:|||:.|||.|.|:||:||||...:.
pombe   123 VLVTLLLGNVIVNETLPIVFDSIIGGGWPAVLISTAMIVIFGEVIPQATCVRYGLSIGAKLEPIV 187

  Fly   310 KTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTND--VNDLDKNEVNIISGALELR 372
            ..:|.:..|::||.:.|||..|||....:|.:..||.||.:..|  ::.|:::||.||:..|:||
pombe   188 LFMMYLLWPIAYPTALILDACLGESQSTMYKKSGLKTLVTLHRDLGIDKLNQDEVTIITAVLDLR 252

  Fly   373 KKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVY-DGDRKNIVTLLYIKDLAFVDTD 436
            :|....:||.|.|.|.|.:|.:||.:.:.||:.:|||||||: .|...:.:.:|..|.|...|.|
pombe   253 EKHAESIMTPIEDVFTLPMDRILDEDLIGEIICAGYSRIPVHKPGFPHDFIGMLLTKTLIGYDPD 317

  Fly   437 DNTP-----LKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVG 496
            |..|     |.||.:.:.|       ...||:: |..:||. .|:..:    :...|:| :..:|
pombe   318 DKWPVGKFALATLPQTWPN-------TSCLDLL-NYCQEGK-SHMILI----SNSPGEP-HGAIG 368

  Fly   497 LVTLEDVIEELIQAEIVDETDVFVD 521
            ::||||:|||||..||:|||||::|
pombe   369 VITLEDIIEELIGEEIIDETDVYID 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
uex	NP_001104390.2	DUF21	188..361	CDD:279876	65/176 (37%)
		CBS_pair_CorC_HlyC_assoc	384..506	CDD:239963	41/127 (32%)
		CAP_ED	<604..>650	CDD:294041
SPCC4B3.03c	NP_588087.1	DUF21	64..241	CDD:279876	65/176 (37%)
SPCC4B3.03c	NP_588087.1	CBS_pair	265..373	CDD:301603	37/121 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	118	1.000	Domainoid score	I1489
eggNOG	1	0.900	-	-		E1_COG1253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000343
OrthoInspector	1	1.000	-	-		oto100931
orthoMCL	1	0.900	-	-		OOG6_100176
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X235
TreeFam	0	0.000	Not matched by this tool.
	7	6.710