Protein Alignment uex and cnnm-2

DIOPT Version :10

• Sequence 1: NP_001104390.2
• Gene: uex / 5740320
• FlyBaseID: FBgn0262124
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: NP_001361958.1
• Gene: cnnm-2 / 181129
• WormBaseID: WBGene00019869
• Length: 760
• Species: Caenorhabditis elegans
• Alignment Length: 790
• Identity: 246/790 - (31%)
• Similarity: 380/790 - (48%)
• Gaps: 155/790 - (19%)

  Fly    58 IVGIRLEDETVETKN-------GIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPA 115
            :.|:|:|.: |:...       |...|..:.|....:||.|||....:|||:      ..|:.
 Worm    29 VSGVRIESD-VDASGFLGYGDAGELLVEANTEVDLVIFGHGLENVEMVTFTD------SVCVT-- 84

  Fly   116 TDLFTPIEVSSNGF------SALYSVKFPSFINEFFICAKTAEKTTNHSKAATTTPLEHQG---- 170
                :...||.:.|      ..::...|.::...:.||.|:                |..|
 Worm    85 ----SEFNVSESTFYIHKDMKIVFKYAFVAWPQPWRICLKS----------------ECHGLIQI 129

  Fly   171 NSDFLKIK----TFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKK 231
            :.|...|:    |.|..:|||....|:......|||.|||.||||::...||.||..:|:::|||
 Worm   130 DDDRTWIQAVQSTHETFMPVWAQCAILCLLFSISALCSGLTLGLMALTPQELSILMKSGSQREKK 194

  Fly   232 YASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLTSGLFAVIFSTLAIVLFGEITPQAVCSR 296
            :|:.|.|:|..||.|||::::.||:||:..|:|.|.|..||.|.:.||:.||:||||.||::|.:
 Worm   195 HAAAIYPIRCHGNRLLCTVIIMNVIVNTGITLLFDDLAEGLIAFVASTVGIVVFGEILPQSICVK 259

  Fly   297 HGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVT--NDVNDLDK 359
            :|||:||.||.:||..|.:..|:::|:.:||||..|.:| :|.||.|:.|::::.  ||..|:|.
 Worm   260 YGLAVGANTIFITKFFMFLLFPITWPLGKILDKYAGVDI-DVVNRSRMVEMLKMNMENDACDIDL 323

  Fly   360 NEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKN-IVT 423
            :.:.|..||:||.||:|.||||.|:|.||||.|.:|:.||:::|.:|||:||||::|:.:| :..
 Worm   324 STLKIAIGAMELTKKSVRDVMTDIDDVFMLSEDQVLNAETMTKISDSGYTRIPVFEGNNRNKVKN 388

  Fly   424 LLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFV--------H 480
            |||:.|||.:..|:|..:|.:..|.:..:..|.|...|..:.::||.|.. |:|.|        |
 Worm   389 LLYVSDLALIGKDNNITVKAVARFNKRRLRIVDESMPLTALMDEFKLGDY-HLAMVAKATEVKKH 452

  Fly   481 RVNNEGDG--DPF-----------------------YETVGLVTLEDVIEELIQAEIVDETDVFV 520
            ......||  |.|                       ...|||:||||:.|||:||||.||||.:|
 Worm   453 HHGKFADGTVDSFILKSMKLVEATMMPQVENPEDHPVTLVGLITLEDITEELLQAEITDETDCYV 517

  Fly   521 --DNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLL 583
              |.:.|.|.|..||:....|..  |.::.|:|..:...|.::|......|..           :
 Worm   518 TDDAQKKRRTNTSKKSAAELFCS--EKKSERLSLHMLEMTEKWLLEKTPLFGN-----------M 569

  Fly   584 NQDVFHNIKTKG---------KSKDDP-SLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGP 638
            |...|.|:..:.         |:...| :|.:|..|.....|:|||||:..:...::.|:||.||
 Worm   570 NPKAFENLIQRNIREVLIVPPKNSTSPGTLNLFEAGVMSKRFLLILEGKATIRFNEKDLIFECGP 634

  Fly   639 FTYFGTQALVPNVVIDSPTQMGSLQSLNMDSKIRQS------FVPDYSVRAISDVIYITIKRVLY 697
            :|.|| :|:              |:.:.|....|:.      |:|||::.......::.|.....
 Worm   635 WTCFG-EAI--------------LEKMEMCISDRKEPSTGFFFLPDYNLTVSGPCRFLQISTSSL 684

  Fly   698 LTAKKATLLEKSRKSGTFSSETFDDEVERLLHSITENEKPSCFAQNQSTRRLSNRSINSSPTNMN 762
            |.:.:.|...|..::...|. |.||:.                  ...||:.|  .::|||.:..
 Worm   685 LHSLRITQFVKEIRTPKISI-TSDDDF------------------GSPTRKAS--ILDSSPNSRK 728

  Fly   763 RSPDFVYNSV 772
            ||...|.||:
 Worm   729 RSSTSVMNSL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
uex	NP_001104390.2	TlyC	187..>517	CDD:440865	150/365 (41%)
		CAP_ED	<604..>650	CDD:469590	17/45 (38%)
cnnm-2	NP_001361958.1	TlyC	147..>514	CDD:440865	152/368 (41%)